Synopsis Felodipine is a dihydropyridine calcium antagonist which may be administered once daily in an extended release (ER) formulation. As monotherapy in older patients with mild to moderate essential hypertension, felodipine ER once daily provides effective control of blood pressure (BP). The drug ...
Felodipine ER is an effective drug for the treatment of all grades of essential hypertension, and can be used both as monotherapy and in combination with other antihypertensive agents. Further clinical experience should fully establish the long term tolerability of felodipine ER and consequently its pl...
Felodil ER information about active ingredients, pharmaceutical forms and doses by Sandoz, Felodil ER indications, usages and related health products lists
英文别名:Perfudal;Plendil;Plendil ER;Splendil;Renedil; CAS号:86189-69-7 分子式:C18H19Cl2NO4 分子量:384.25400 结构式: 精确质量:383.06900 PSA:64.63000 LogP:4.29310 [1] 物化性质 密度:1.277 g/cm3 沸点:471.5ºC at 760 mmHg 闪点:239ºC [1] 分子结构数据 1、 摩尔折射率:95.78 2、 摩尔...
TEM 结果显示对照组 5xFAD 小鼠小胶质细胞中 ER 体积扩大,而LIPUS+Felodipine@LND处理改善了 ER 结构的扩张变化(图 2I)。这些结果表明,LIPUS+Felodipine@LND处理促进了Felodipine向大脑的递送,使ER URP中的细胞信号传导从Perk-eIF2 轴转向Perk-Nrf2轴,从而缓解了小鼠的焦虑样行为,并提高了其认知能力(图2J)。
D29UNCHANGED BLOOD LIPIDS AND THYROID FUNCTION AFTER TREATMENT WITH FELODIPINE ER. A 12-MONTH PLACEBO CONTROLLED TRIALD29UNCHANGED BLOOD LIPIDS AND THYROID FUNCTION AFTER TREATMENT WITH FELODIPINE ER. A 12-MONTH PLACEBO CONTROLLED TRIALFelodipine ERLipids...
felodipine ERhypertensionleft ventricular hypertrophypatientsThe aim of the study was to evaluate the efficacy over 1 year of felodipine ER 5 and 10mg once daily (od) in 12 Caucasian patients with left ventricular hypertrophy secondary to primary hypertension. After a placebo period of 20 days, a...
In this randomised, cross-over study, in nine healthy males given felodipine ER 10 mg PO 200 ml grapefruit juice was found to increase the plasma levels of... J Lundahl,CG Reg?Rdh,B Edgar,... - 《European Journal of Clinical Pharmacology》 被引量: 283发表: 1995年 Combined enalapril an...
The efficacy and tolerability of extended-release felodipine (felodipine-ER) and nifedipine gastrointestinal therapeutic system (nifedipine GITS) were compared in a multicenter, prospective, open-label clinical trial of 277 patients with mild-to-moderate uncomplicated essential hypertension (sitting diastolic...
After 4 weeks of treatment, seated mean DBP values had decreased from 105卤6 mm Hg to 89卤7 mm Hg in the felodipine ER group and from 105卤6 mm Hg to 92卤8 mm Hg in the nifedipine R group. The mean reduction was 3 mm Hg greater with felodipine ER than with nifedipine R (95% ...