Feedback regulation of TGF-beta signaling. Acta Biochim. Biophys. Sin. (Shanghai) 2018, 50, 37-50. [CrossRef] [PubMed]Yan X, Xiong X, Chen Y. Feedback regulation of TGF- β signaling. Acta Biochim Biophys Sin (Shanghai). 2017. doi: 10.1093/abbs/gmx129.Yan X, Xiong X, Chen YG...
The regulation of TGF-beta/SMAD signaling by protein deubiquitination. Protein Cell. 2014;5:503–17. https://doi.org/10.1007/s13238-014-0058-8. Article CAS PubMed PubMed Central Google Scholar Cao Y, Zhang L. A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple ...
GATA-4 is a granulosa cell factor employed in inhibin-alpha activation by the TGF-beta pathway. Part of heterodimeric inhibin, inhibin-a is crucial for mammalian ovarian function. Regulation of inhibin-a expression in granulosa cells is both endocrine... Anttonen,M - 《Journal of Molecular Endoc...
Attenuation of daf-2 insulin-like or daf-7 TGFbeta-like si... Mak,Y H. - 《Development》 被引量: 263发表: 2004年 Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making Differentiation of uncommitted T cells ...
Regarding the regulatory mechanisms of PN-1 expression in breast cancer cells, we elucidated that epidermal growth factor (EGF), could induce PN-1 up-regulation through the activation of EGFR/PKCδ/MEK/ERK signaling pathway in breast cancer cells, resulting in the up-regulation of EGR1, a ...
of signaling molecules and transcription factors, including SNAIL, zinc-finger E-box-binding homeobox 1 (ZEB1) and basic helix-loop-helix transcription factors, as well as a diverse array of cytokines and growth factors including transforming growth factor-β (TGFβ).6,15 Currently, targeting EMT...
(E) The effect of miR-586 on the interactions of β-catenin with TCF4 in the indicated cells, as determined by IP. ∗p < 0.05. miR-586 can suppress multiple Wnt/β-catenin signaling antagonists To elucidate the mechanisms underlying the regulation of miR-586 on Wnt/β-catenin signaling,...
TGF-β promotes the expression of miR-577, and miR-577 participates TGF-β-mediated cancer metastasis. Mechanistically, TGF-β activates miR-577 via NF-κB-mediated transcription, and miR-577 enhances TGF-β signaling by targeting the serumdeprivation proteinresponse (SDPR), which directly interacts...
Overall, the findings strongly suggest that autophagy and TGF play key balancing roles in HTM cell function and regulation of fibrotic response. Finally, these findings point to autophagy and aggregated proteins as potential new therapeutic targets for reversing or preventing HTM cell death in XFG. ...
Role of a Jak/STAT Pathway in Regulation of the Adipose-Specific Promoter. J. Biol. Chem. 1995, 270, 16449–16457. [Google Scholar] [CrossRef] Chabab, A.; Nicolas, J.C.; Sultan, C. Aromatase Activity in Human Skin Fibroblasts: Characterization by an Enzymatic Method. J. Steroid ...