Febrile neutropenia Febrileneutropenia(FN) is defined by the following criteria: • A single oral temperature ≥38.3°C (101.0°F) or an oral temperature ≥38.0°C (100.4°F) sustained for >1hour or that occurs twice within a 24-hour period. ...
BackgroundThere are no standard criteria for when to discontinue antibiotics in children with febrile neutropenia (FN), but it is now common to discontinue antibiotics and discharge patients with an absolute neutrophil count (ANC) ≤ 500 /mm3. The purpose of this study was toevaluate the outcome...
SummaryFebrile Neutropenia is a relevant factor for mortality after chemotherapy. Dependent upon factors like duration of neutropenia (鈮 7 d means high-risk situation), patient- and disease specific criteria e.g. defined in the MASCC score (Multinational Association of Supportive Care in Cancer) ...
2013, "Procalcitonin as a marker of infection in febrile neutropenia: A systematic review". Modern Chemotherapy, vol. 2, no. 1, pp. 8-14.Boysen AK; Jensen BR; Poulsen L;.Procalcitonin as a marker of infection in febrile neutropenia: A systematic review.Modem Chemotherapy.2013.8-14...
Aggressive chemotherapy has a deleterious effect on all components of the defense system of the human body. The resulting neutropenia as well as injury to the pulmonary and gastrointestinal mucosa allow pathogenic micro-organisms easy access to the body.
Schwenkglenks M, Bendall KL, Pfeil AM, Szabo Z, Pettengell R. External validation of a risk model of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma. Leuk Lymphoma. 2013; 54 :2426–32.Schwenkglenks M, Bendall KL, Pfeil AM, Szabo Z, Pettengell R. Ex- ternal ...
Since the mid-1980s, many paediatric centres commonly discharge patients before complete bone marrow recovery, provided that patients meet certain low-risk criteria and do not exhibit any clinical or biological evidence of bacterial infection. However, a few prospective randomised studies have been ...
www.nature.com/scientificreports OPEN Machine learning improves the prediction of febrile neutropenia in Korean inpatients undergoing chemotherapy for breast cancer Bum‑Joo Cho1, Kyoung Min Kim2, Sanchir‑Erdene Bilegsaikhan3 &Yong Joon Suh4* Febrile neutropenia (FN) ...
In this review, 20 different combinations of criteria were used to define febrile neutropenia. These data could not be directly assessed to explore their relationship with the diagnostic value of the biomarkers, but as the depth of neutropenia and peak, and duration of temperature may affect the ...
Adverse events such as neutropenia and FN were assessed via routine blood tests according to the Common Terminology Criteria for Adverse Events (CTCAE 3.0). Statistical analysis No formal sample size estimation was conducted because this was an exploratory study. Efficacy and safety were analyzed ...