(1) develop better treatments or prevention strategies for AD, or, as a strategy to identify subpopulations at risk for developing AD, or (2) resolve clinically difficult differential diagnoses (e.g., frontotemporal dementia (FTD) versus AD) where the use of PET Aβimaging appears to improve...
520 were screened for C9ORF72 mutations. In 38 patients a mutation was detected. The mutation carriers who had undergone a cerebral FDG-PET scan at study inclusion (n = 22) were included in the present study. A non-mutation carrier from the FTLDc was matched ...
AMYLOID PET HAS GREATER CLINICAL IMPACT THAN FDG PET IN THE DIFFERENTIAL DIAGNOSIS OF AD AND FTDdoi:10.1016/j.jalz.2014.05.027Pia M. GhoshCindee MadisonMiguel SantosKristin NortonSuzanne BakerAdam L. BoxerHoward J. RosenZachary A.A. Miller...
(2016). Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD. Ann. Clin. Transl. Neurol. 3, 740-751. doi: 10.1002/acn3.330Tosun, D. et al. Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD. Ann. Clin. Transl. ...
SUVR was lower in the AD group for the posterior cingulate (M = 1.09) compared to the FTD group (M =1.42). As shown in Figure 4, this region provided complete separation between groups. Conclusions These data suggest that MR-less analysis of FDG-PET corresponds strongly to the clinical ...
METHODS: Fifty-two patients and 19 control subjects underwent both (11)C-DTBZ and (18)F-FDG PET scans. Seven had the clinical diagnosis of frontotemporal dementia (FTD), 25 had Alzheimer's disease (AD), and 20 had dementia with Lewy bodies (DLB). DTBZ scans provided mapsof K(1) and...
Twenty-four patients bearing clinically diagnosed AD ( n = 16) and FTD ( n = 8) underwent [ 18F] FDG-PET/CT brain scan. Four nuclear medicine physicians with varying expertise in neuroimaging read each scan according to: visual analysis; automated analysis computed by BRASS Hermes software; ...
The bvFTD phenocopy syndrome: a case study supported by repeated MRI, [18F]FDG-PET and pathological assessmentBehavioral variant frontotemporal dementiamisdiagnosisneuropsychiatryphenocopy syndromediagnostic distinction of bvFTD and primary psychiatric diseases...
Comparing brain structural MRI and met- abolic FDG-PET changes in patients with ALS-FTD: `the chicken or the egg?' question. J Neurol Neurosurg Psychiatry. 2015;86: 952-8. doi:10.1136/jnnp-2014-308239.Rajagopalan, V., & Pioro, E. P. (2015). Comparing brain structural MRI and ...
Temporal pole, inferior frontal gyrus, insula and nucleus accumbens FDG-PET hypometabolism in the 7 bvFTD patients impaired on social tasks.Chiara, CeramiAlessandra, DodichSandro, IannacconeAlessandra, MarconeGiada, LettieriChiara, CrespiLuigi, Gia...