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there continues to be uncertainty regarding the economy, general business conditions, access to capital and the marginal cost of such capital for the Group and its counterparties and as well as consumer purchase patterns, which could affect the Group's financial position, results of operations and ...
1 Opinion In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Sistema Joint Stock Financial Corporation and its subsidiaries as of December 31, 2014 and 2013, and the results of their operations and their cash ...
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Results of a Phase III Trial of Prolgolimab with Chemotherapy as First-Line Therapy for Patients with Advanced Non-Squamous NSCLC: DOMAJOR III期DOMAJOR临床试验结果:Prolgolimab联合化疗作为晚期非鳞状NSCLC患者的一线治疗方案 汇...
Results Postnatal development is associated with an age-dependent increase of IgG1 galactosylation and sialylation To characterize the Asn-297 glycovariation in murine IgG1 during the progression from birth to adulthood, we analysed the frequency distribution of galactosylated and sialylated species during...
Fucosylation and sialylation of the IgG1 Fc glycan are the determinants of binding to Type II FcγRs. Core fucosylation and sialylation results in destabilization of the Fc, enabling sampling of a 'closed' conformation that can engage Type II FcγRs [9]. One well characterized activity ...
Of note, with respect to infection, the antibody-mediated triggering of FcγR may have contrasting effects: On the one hand, the opsonization of pathogens that normally evade degradation in lysosomes like Legionella pneumophila and Mycobacterium bovis bacillus Calmette–Guérin results in targeting ...