R. & Woof, J. M. Human antibody effector function. Adv. Immunol. 51, 1–84 (1992). CAS PubMed Google Scholar Matsumiya, S. et al. Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1. J. Mol. Biol. 368, 767–779 (2007). CAS PubMed ...
An amino acid motif that enables proteins to recognize phosphatidylinositol-3,4,5-trisphosphate. Plasmablasts A short lived, dividing cell population that can develop from any type of activated B cell and that is characterized by its capacity to secrete antibodies. ...
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Treatment GroupAKR-001 QWAKR-001 Q2W 7 mg (n = 6)21 mg (n = 6)70 mg (n = 6)140mg (n = 5)7 mg (n = 6)21 mg (n = 6)70 mg (n = 6)140 mg (n = 6) Glucose 4 (−12, 22) 5 (−11, 24) −23, (−35, −9) −20 (−32, −6) −3 (−18...
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The FcεRI complex forms a high-affinity cell-surface receptor for the Fc region of antigen-specific immunoglobulin E (IgE) molecules. FcεRI is multimeric and is a member of a family of related antigen/Fc receptors which have conserved structural featur
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2. isolated and determined the complete nucleotide sequence of cDNA clones termed pFC24 and pFC113 encoding the beta1 Fc(gamma)R receptor. 3. Shown by Northern analysis the presence of multiple FcR transcripts in different cell types, these variant transcripts are termed beta2 and alpha. ...