The inbred, albino Osborne-Mendel (OM) rat is a model of diet-induced obesity, becoming obese on a high-fat (36% fat) diet (Schemmel et al., 1970). A high incidence of spontaneous tumors has been noted in the this rat, including thyroid carcinoma (33%), adrenal cortical tumors (94...
This is a tough question to answer without being able to see and touch these lumps, but I can give you a few of my thoughts as to what might be going on. My first concern would be that these could be some type of mammary tumors. However, it's a little bit odd to have two pop...
Peptides and proteins are widely used to treat a range of medical conditions; however, they often have to be injected and their effects are short-lived. These shortcomings of the native structure can be addressed by molecular engineering, but this is a c
"Dietary consumption of omega-3 fatty acids can lead to the formation of these substances in the body and may have some beneficial effects," said study leader Aditi Das, a professor of comparative biosciences and an affiliate of biochemistry at UI. "If you have cancer, you want something con...
characterized and RNA probes have been used in nuclease protectionassays to show that some classes of human tumors exhibit increased levels of desaturase mRNA. A structural gene for Δ9 desaturase of yeast (OLE-1) also has been isolated and characterized; rat liver Δ9 desaturase can effectivel...
(Kidney) Cancer; Renal Pelvis and Ureter, Transitional Cell Cancer; Respiratory Tract Carcinoma Involving the NUT Gene on Chromosome 15; Retinoblastoma; Rhabdomyosarcoma; Salivary Gland Cancer; Sarcoma, Ewing Family of Tumors; Sarcoma, Kaposi; Sarcoma, Soft Tissue; Sarcoma, Uterine; Sezary Syndrome; ...
section VI). Tumor volume was less than 50% of controls in the 2 mM infused rats. However, histology and TUNEL reactivity of the remaining tumor indicated that this may be an under-estimate of residual viable tumor as substantial areas of treated tumors showed characteristics of necrotic tissue...
In jurisdictions that forbid the patenting of methods that are practiced on the human body, the following restrictions are intended: (1) the selecting of a human subject shall be construed to be restricted to selecting based on testing of a 10 biological sample that has previously been removed ...
Over the last two decades, bile acids have been recognized as pivotal signaling molecules in NASH pathogenesis that enable fine-tuned gut-liver communication from the liver, the site of bile acid production, to the intestine, the site of nutrition sensing, to virtually throughout the body, where...
EPA and DHA when carried by Non-HDL lipoproteins, only in patients with hormone-receptor-negative tumors. These results have been observed in a clinical study and confirmed by an in vitro approach. Experiments are currently underway on large cohorts of breast cancer patients to confirm our hypothe...