Factors determining the prognosis of cases with free colorectal perforation were examined. Between 1982 and 1995, 34 patients with free colorectal perforation visited our department. These 34 cases did not have colorectal perforation caused by trauma. The 34 cases were divided into two groups: 24 ...
Prognosis It is widely considered that fatty liver is an entirely benign lesion reversible with abstention from alcohol. Fat starts to accumulate in the liver after as little as one weekend of heavy drinking in nonalcoholic human volunteers.237 Fortunately the reverse seems to hold true, and in ...
Studies have not yet thoroughly examined whether the criteria for MAFLD performs equally well or better than the NAFLD criteria for identifying patients with at least moderate fibrosis. NAFLD encompasses several stages of increasing severity and worsening prognosis, from simple hepatic steatosis to nona...
Introduction Fatty liver is a common 'liver disease' often free of symptoms or complaints but might even lead to severe stages. It is characterized by lipid deposition in hepatocytes both, for alcoholic as well as and non-alcoholic fatty liver. An additional inflammatory reaction results in - ...
COVID-19, together with other liver diseases [15] or other metabolic conditions such as obesity and type 2 diabetes [16]. Although many of these topics have been extensively described elsewhere, the overall impact of MAFLD on research activity has not been objectively and comprehensively assessed...
Non-alcoholic fatty liver disease (NAFLD) has been shown to influence breast cancer progression, but the underlying mechanisms remain unclear. In this study, we investigated the impact of NAFLD on breast cancer tumor growth and cell viability through the
value of a liver biopsy for the diagnosis of NAFLD in routine clinical practice is controversial, especially in the presence of a generally good prognosis for most patients with NAFLD, the lack of an established form of effective therapy, and the risks and costs associated with the liver biopsy...
This problematic definition has prompted a consensus to rename and redefine adult NAFLD associated with metabolic dysregulation to metabolic (dysfunction)-associated fatty liver disease (MAFLD). Similarities, distinctions, and differences exist in the causes, natural history, and prognosis of fatty liver ...
Left unmanaged, the disease can progress through increasing stages of hepatic fibrosis, leading to cirrhosis and associated complications, including hepatocellular carcinoma (HCC) (Box 1).4,5 Fatty liver disease causes quality of life impairments, which worsen with disease progression and are compounded...
(MODS). Take alcohol for example, alcohol is mainly eliminated by CYP2E1 of liver and its mechanism of APAP intoxication is divided into three stages: at the first stage alcohol competes the receptors for CYP2E1 with APAP in the liver and the concentration of NAPQI will reduce during the ...