Article PubMed PubMed Central Google Scholar Younes, R. et al. Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach? Gut https://doi.org/10.1136/gutjnl-2020-322564 (2021). Ludwig, J., Viggiano,...
P. Nonalcoholic fatty liver disease: pathogenesis and disease spectrum. Annu. Rev. Pathol. 11, 451–496 (2016). This review describes the liver pathophysiology that underlies NAFLD. Article CAS PubMed Google Scholar White, D. L., Kanwal, F. & El-Serag, H. B. Association between non...
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that may progress into, in the absence of proper treatment, severe liver damage. While the optimal pharmacotherapy for NAFLD remains uncertain and the adherence to lifestyle intervention
2021 Metabolic Efficacy of Time-Restricted Eating in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Lili Liu, The Journal of Clinical Endocrinology & Metabolism, 2022 LONG-TERM LIFESTYLE INTERVENTIONS IN MIDDLE-AGED AND ELDERLY MEN WITH NONALCOHOLIC FATTY LIVER DISEASE ...
This term could be used to describe cases of FLD in which there is an overlap of previously described entities, e.g. S-MAFLD and O-MAFLD, or those and GAFLD. The development of fatty liver disease can be impacted by many different pathways and their overlap (Fig. 1). As detailed in...
In the long-term HFD model with serum and liver collection after treatment for 14, 28, 34, 46, or 82 weeks, we observed that the liver damage worsened over time as shown by our acquired histological images (Figure S1K). The BA profiling of liver tissues showed that concentrations of HCA...
Article CAS PubMed Google Scholar Tugwood JD, Holden PR, James NH, Prince RA, Roberts RA: A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARalpha: implications for species differences in re...
Article CAS PubMed Google Scholar Strand E, Bjorndal B, Nygard O, Burri L, Berge C, Bohov P, Christensen BJ, Berge K, Wergedahl H, Viste A, Berge RK: Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of ...
Joshi SR reported that Asian Indians consists of smaller body size but suffer from central obesity (higher waist to hip ratio) and higher subscapular-to-triceps skin fold ratio when compared with their British counterparts, hence the term thin-fat Indian7. Furthermore, it also reflected in ...
Nonalcoholic fatty liver disease (NAFLD) affects a large population with incompletely defined mechanism(s). Here we report that Kindlin-2 is dramatically up-regulated in livers in obese mice and patients with NAFLD. Kindlin-2 haploinsufficiency in hepato