中药多糖防治非酒精性脂肪性肝病作用机制研究进展 非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是指除酒精和其他明确的肝损因素所致的,以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征[1]。全球近25%的人口受到NAFLD和/或其并发症的影响,使其成为最常见的慢性和进行性肝病,模型预测NAFLD在...
B. et al. High-risk coronary plaque at coronary CT angiography is associated with nonalcoholic fatty liver disease, independent of coronary plaque and stenosis burden: results from the ROMICAT II trial. Radiology 274, 693–701 (2015). Article PubMed Google Scholar Bonapace, S. et al. ...
doi:10.1016/S0168-8278(20)30798-4Andrea DalbeniFilippo CattazzoAnna MantovaniMichele BevilacquaEmmanuel TsochatzisJournal of Hepatology
Association of liver fibrosis risk scores with clinical outcomes in patients with heart failure with preserved ejection fraction: findings from TOPCAT Aims: Non-alcoholic fatty liver disease leads to progressive liver fibrosis and appears to be a frequent co-morbid disease in heart failure with preser...
Background: Non-alcoholic fatty liver disease has been a significant risk factor for hepatocellular carcinoma. In the study, we aimed to identify the key genes associated with the transition from non-alcoholic fatty liver disease to hepatocellular carcinoma through bioinformatics analysis. Methods: The...
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver condition that affects a quarter of the global adult population. To date, only a few NAFLD risk prediction models have been developed for Chinese older adults aged ≥ 60 years. Thi
nutrients Article Nonalcoholic Fatty Liver Disease Is Exacerbated in High-Fat Diet-Fed Gnotobiotic Mice by Colonization with the Gut Microbiota from Patients with Nonalcoholic Steatohepatitis Chien-Chao Chiu 1, Yung-Hao Ching 2, Yen-Peng Li 3, Ju-Yun Liu 4, Yen-Te Huang...
NAFLD is a common disease in Western society and ranges from steatosis to steatohepatitis and to end-stage liver disease. The molecular mechanisms that cause the progression of steatosis to severe liver damage are not fully understood. One suggested mechanism involves the oxidation of biomolecules by...
A relationship between liver diseases and serum vitamin B12 levels was observed in previous reports. The purpose of this study was to determine if a similar relationship existed between vitamin B12 and nonalcoholic fatty liver disease (NAFLD), a common chronic liver disorder.A total of 45 consecut...
HEBT reversed ethanol-induced oxidative stress in the liver, reduced lipoperoxidation, normalized GPx, GST, SOD and Cat activity, and GSH and total ROS levels. The reverser effect of HEBT was observed upon ethanol-induced increases in the levels of plasma and hepatic triglycerides, plasma ...