The plasma aspartate transaminase (AST), alkaline phosphatase (ALP), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were
Most of the other liver blood tests (e.g., bilirubin and alkaline phosphatase) are usually normal in patients with NASH. Gammaglutamyltranspeptidase (GGTP), however, is typically moderately elevated. Serum ferritin (a protein involved in iron storage and inflammation) can be significantly elevated,...
The diets containing high fat also had a higher ME of 3,000 kcal/kg of feed while the other 2 diets with normal fat had a regular lower amount of ME (2750 kcal/kg). Hen-day egg production (HDEP), ADFI, BW, egg weight, plasma enzymes indicating liver damage (alkaline phosphatase [...
Citation51,Citation52 The “Pediatric NAFLD fibrosis score” (based on ALT, GGT, platelet counts, and alkaline phosphatase) has been also developed and seems useful in predicting advanced liver fibrosis, although larger validation is needed.Citation53,Citation54 Of interest, recent promising studies ...
Gut-derived bacterial lipopolysaccharide (LPS) and subsequent hepatic toll-like receptor 4 (TLR4) activation have been recognized to be involved in the onset of diet-induced nonalcoholic fatty liver disease (NAFLD), but little is known about the variatio
Liver disease is a high incidence disease in Asia [2,3,4]. There is strong evidence that a sedentary lifestyle and unhealthy dietary habits (especially those with high fat and high salt) are setting the stage for the prevalence of obesity and nonalcoholic fatty liver disease (NAFLD) in ...
We also collected data on liver and renal function tests including alanine aminotransferase (ALT), alkaline phosphatase (ALP), glutamyltransferase (GGT), total protein (TP), albumin (ALB), urea, uric acid, creatinine was also measured. Diagnosis of MS and NAFLD The study endpoint was the ...
Researchers found that IF resulted in a fundamentally reduced liver mass and altered the levels of liver-associated biochemical markers in blood samples from mice, including the blood glucose levels and alkaline phosphatase. Benefits with IF were also observed in some RCTs of mice with NAFLD, and...
We showed that genetic variants within the MTARC1 locus are associated with liver enzymes, liver fat, plasma lipids, and body composition, and these associations are attributable to the same causal variant (p.A165T, rs2642438 G>A), suggesting a shared mechanism. We demonstrated that increased ...
5.3 Nonalcoholic fatty liver disease (NAFLD)-associated liver fibrosis The role of NKT cells in high fat diet (HFD)-induced obesity, insulin resistance, and fatty liver disease has been extensively investigated in C56BL/6 mice, but the results have been controversial [55–59]. In addition, ...