The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio has been considered an alternative marker for hepatic steatosis. However, few studies have investigated the association of the ALT/AST ratio with non-alcoholic fatty liver disease (NAFLD) in nonobese people.A total of 12,127...
(AST/ALT) ratio,lowered albumin,and platelet were risk factors for progressive fibrosis of NAFLD.In addition,NFS was positively correlated with duration of diabetes,waist circumference,SBP,glycated albumin (GA),and GA/HbA1c(all P<0.01),and negatively with red blood cell count,hemoglobin,white ...
AST/ALT ratio has also been primarily used in cohorts of patients with chronic hepatitis C [20]. The diagnostic accuracy of APRI and AST/ALT ratio has been reported to be low for diagnosing advanced fibrosis in patients with NAFLD (AUROC of 0.74 for the differentiation of F3 liver fibrosis)...
(B) Representative H&E and oil red O staining of liver sections; scale bars, 100 μm. (C–F) Steatosis score based on the histological analysis (C), the ratios of liver weights to body weights (D), the levels of serum ALT and AST (E), and the levels of hepatic TC and TG (F...
NFS4 = 1.675 + 0.037 × age (years) + 0.094 × BMI (kg m−2) + 1.13 × T2DM + (0.99 × AST:ALT ratio) (0.013 × platelet (109per l)) (0.66 × albumin (g dl−1)) ...
Fig. 2.β-PAE attenuates weight gain, liver injury and lipid accumulation in HFD-fed rats. (A) Body weight; (B) Liver index; (C) Food intake; (D–I) Serum levels of ALT, AST, HDL-C, LDL-C, TG and TC; (J–L) Liver levels of TG, TC and NEFA. Data are presented as the ...
Obesity, diabetes mellitus, thrombocytes ≤200×103/L, advanced age and AST/ALT ratio ≥0.8 are the risk factors of advanced fibrosis. 展开 关键词: BARD score liver biopsy liver fibrosis NAFLD fibrosis score non-alcoholic fatty liver disease ...
(Sarstedt, Marnay, France). Plasma was separated and stored at −20 °C until assay. Adiposity index was calculated as the ratio between epidydimal fat pad weight and body weight. Liver samples were collected for histopathology or stored at −80C until metabolomic profiling or gene ...
Liver to spleen ratio LDL: Low density lipoprotein-cholesterol MRS: Magnetic resonance spectroscopy TB: Total bilirubin TC: Total cholesterol TG: Triglyceride TNF-α: Tumor necrosis factor-α VLDL: Very low density lipoprotein WHR: Waist/hip ratio WM: Western medicine ...
Comparing ALT with AST levels gives your doctor more information about the health of your liver. The AST-to-ASL ratio can help your doctor figure out how severe the liver damage is and what might have caused it. To find out what type of liver disease you have, your doctor might also te...