Moreover, NO2-FAs are considered stable and ubiquitous deposits of NO. This is because NO and its derived species have a very short half-life and perform their function in the vicinity of the place where they are generated. In an aqueous environment, if the concentration of NO2-FAs exceeds...
. Elevated serum cholesterol and triglyceride concentrations have been reported to be a risk factor for DR [5,6], and it has been suggested that permeability changes in the retinal microvasculature result in extravascular accumulations of lipoprotein deposits with a consequent loss of function in ...
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The International Prostate Symptom Score (IPSS), PV and post‐voided residual urine volume (PVR) were significantly greater in men with higher NAFLD grades. Conversely, the maximum urinary flow rate (Qmax) and IIEF‐5 score were lower in men with higher NAFLD grades. The NAFLD grade, ...
In mice, two independent Atxn2-knock-out (KO) lines confirmed phenotypes of obesity (30, 31), with excessive liver fat and glycogen deposits, insulin resistance, and dyslipidemia also being noted by the age of 6 months. Thus, even in the absence of high-fat-diet and within the short lif...
Regarding renal function, serum creatinine increased in the ZDF animals compared to the ZL rats, whereas it decreased in the diabetic groups treated with metformin alone or in combination with the CC-supplemented diet (Table 2). Urine glucose decreased in metformin-treated animals compared to all ...