A HIGH-FAT diet is likely to play a critical role in the development of breast cancer, a study shows. The best explanation for the disease, which claims 13,000 lives a year in Britain, is that a fatty Western diet depletes the breast tissue of an essential nutrient that protects against...
Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted. Me...
Bruce F Kimler2 and Stephen D Hursting3 Abstract Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast ...
ATrial schematic for establishing an HFD-fed NAFLD-breast cancer mice model.B,CMice on the HFD diet showed accelerated body weight growth (B) and higher body fat rates (C).DIncreased wet weights of adipose tissue were observed.E–HEvaluation of NAFLD revealed that the HFD induced higher live...
Researchers at the University of Illinois (UI) obtained blood samples from a tissue bank and compared those of healthy women with the samples of women who were healthy at outset but later developed breast cancer. They also analyzed additional blood samples from 37 non-obese and 63 obese postmeno...
We have completed separate pilot studies of 3.4 g/day EPA + DHA ethyl esters (4 g Lovaza™) administered for 6 months to explore effects on benign breast tissue risk biomarkers for breast cancer in premenopausal and postmenopausal women at increased risk for breast cancer. Favorable modulat...
the genetic variability of the genes encoding for ChREBP, SREBP and FAS (respectively, MLXIPL, SREBF1 and FASN) is related to breast cancer risk and body-mass index (BMI) by studying 1,294 breast cancer cases and 2,452 controls from the European Prospective Investigation on Cancer (EPIC)...
Omega-3 fatty acid supplements in women at high risk of breast cancer have dose-dependent effects on breast adipose tissue fatty acid composition YEE LD,LESTER JL,COLE RM,et al.Omega-3 fattyacid supplements in women at high risk of breast cancerhave dose-dependent effects on breast adipose ...
Researchers at the University of Illinois (UI) obtained blood samples from a tissue bank and compared those of healthy women with the samples of women who were healthy at outset but later developed breast cancer. They also analyzed additional blood samples from 37 non-obese and 63 obese postmeno...
Obesity is associated with increased recurrence and reduced survival of breast cancer. Adipocytes constitute a significant component of breast tissue, yet their role in provisioning metabolic substrates to support breast cancer progression is poorly unde