(Fig. 5;Ralph et al., 2004). Theapicoplastfatty acid synthesis pathway produces predominantly short-chain (14 and 16 carbons) fatty acids (Ramakrishnan et al., 2012). Eight carbon-chain fatty acids are also modified in the apicoplast by a two-enzyme pathway to generatelipoic acid, which ...
Activated mTOR increases glycolysis and protein synthesis. As a secondary consequence of increased flux through glycolysis, the pentose phosphate pathway provides ribose for nucleic acid synthesis and NADPH for enhanced fatty acid synthesis. Thus, the combination of pAKT and mTOR leads to a cascade ...
Acute infection is known to induce rapid expansion of hematopoietic stem cells (HSCs), but the mechanisms supporting this expansion remain incomplete. Using mouse models, we show that inducible CD36 is required for free fatty acid uptake by HSCs during a
Fatty acid synthase (Fasn) is the key metabolic enzyme that accounts for the terminal catalytic step in fatty acid synthesis, which is hyperactivated in various tumors. In this study, we depicted that Fasn expression was elevated in human colorectal cancer (CRC), which accordingly led to lymphat...
P-307 Fatty acid degradation during in vitro decidualization of human endometrial stromal cells STUDY QUESTION. Is the activity of the β-oxidation pathway, involved in the degradation of fatty acids, modified during in vitro decidualization of human endometrial stromal cells (HESC)? SUMMARY ANSWER....
Fatty acid synthase (FASN) Inhibitors on signaling pathway are available at Adooq Bioscience. Check Fatty acid synthase (FASN) pathway , inhibitors reviews and assay information.
来源期刊 Journal of Clinical Investigation 1/1995 研究点推荐 human subjects tracer studies fatty acid oxidation TRICARBOXYLIC ACID CYCLE 引用走势 2000 被引量:25 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,...
It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a fatty acid biosynthetic pathway in the relict plastid of P. falciparum (known as the apicop...
Figure 1. Fatty acid synthesis and protein myristoylation impact worm mobility and myosin organization (A) Cartoon diagram to indicate the roles of genes involved in the tests. (B–I) GFP images and bar graph showing that reduction of FA biosynthesis and protein myristoylation affect myosin organiz...
Simplified schematic part of the fatty acid pathway known in plants.Wang, Ming LiKhera, PawanK. Pandey, ManishWang, HuiQiao, LixianFeng, SupingTonnis, BrandonA. Barkley, NoellePinnow, DavidC. Holbrook, Corley