[translate] aYou are my happiness of 您是我的幸福 [translate] aAccording to the formula 根据惯例 [translate] aFatty acid oxidation disorder 脂肪酸氧化作用混乱 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语翻译 葡萄牙语翻译 意大利语翻译 荷兰语翻译 瑞典语...
Table 1 Main clinical symptoms and routine blood test results when symptomatic of mitochondrial fatty acid oxidation disorders (FAOD). Most fatty acid oxidation occurs in the mitochondria. Medium- and short-chain fatty acids directly enter the mitochondria. Long-chain fatty acids (LCFA) circulate in...
The range of clinical symptoms seen on presentation with these multiple disorders varies considerably. The biomarkers used to diagnose them may overlap between disorders or be specific for a given disorder. This chapter will present and discuss the disorders of fatty acid oxidation and the carnitine ...
Fatty acid oxidation disorders (FAODs) are potentially fatal inherited disorders for which management focuses on early disease detection and dietary intervention to reduce the impact of metabolic crises and associated spectrum of clinical symptoms. They can be divided functionally into long-chain (LC-FA...
Fatty acid oxidation occurs in mitochondria, peroxisomes and microsomes (Fig. 2). Oxidation may proceed either from the 2nd carbon atom adjacent to the COOH asβ-oxidation, or from the terminal carbon asω-oxidation. The β-oxidation occurs in the mitochondria and the peroxisomes, whereas ω-ox...
Although several clinical trials have evaluated the impact of n-3 polyunsaturated fatty acid (PUFA) on patients with attention-deficit hyperactivity disorder (ADHD), changes in plasma PUFA composition were not always assessed following n-3 supplementation. Furthermore, no reports are available on the...
Review: ω-3 fatty acids produce a small improvement in ADHD symptoms in children compared with placebo. Omega-3-fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology: systematic review and meta-analysis. J Amer Acad Child Adolesc Psychiatry...
(erythrocyte membrane EPA and DHA) and symptoms of depression could be established.(Cai 2017) In another study, supplementation with omega-3 fatty acids in 7- to 14-year-old patients with depression (n=72) or bipolar disorder (n=23) improved fatty acid profiles and symptoms of depression ...
Mitochondrial fatty acid oxidation disorders (FAODs) are caused by defects in β-oxidation enzymes, including very long-chain acyl-CoA dehydrogenase (VLCAD), trifunctional protein (TFP), carnitine palmitoyltransferase-2 (CPT2), carnitine-acylcarnitine translocase (CACT) and others. During prolonged fast...
Patients with very long-chain acyl-CoA dehydrogenase (VLCAD) and long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD)/mitochondrial trifunctional protein (MTP) deficiency, disorders of the mitochondrial long-chain fatty acid oxidation, can present with hypoketotic hypoglycemia, rhabdomyolysis, and cardiomyop...