接着,作者总结了the strengths and limitations for constructing fate maps—schematics representing the developmental potential of specific cells or regions of cells within an embryo at a defined stage, as outlined at the beginning of this review. 13.1 Advances in Cell Imaging for High-Resolution, Non...
Using a combination of focal dye injections and time-lapse imaging, we find that neural crest and dorsal neural tube precursors are present in a broad, crescent-shaped region of the gastrula. Surprisingly, static fate maps together with dynamic confocal imaging reveal that the neural plate border...
Fate maps are schematics or blueprints that show where cell determination is most likely to occur in an embryo at stages of the developmental process. They are used to determine the types of cells that are developing in a certain region, as well as their location within that region. Fate map...
We combine WOT-based inter-time point transport maps \({\pi }_{{t}_{j},{t}_{j+1}}\) with similarity-based intra-time-point transition matrices \({\tilde{T}}_{{t}_{j},{t}_{j}}\) in a global transition matrix T which contains cells from all time points. In the global ...
The aim of this paper is to test two different fate maps for the amphibian blastula with respect to their predictions concerning the process of cell differentiation. The first of these fate maps is the one proposed by Vogt, according to which all three germ layers can be projected on to the...
Fate maps are schematics or blueprints that show where cell determination is most likely to occur in an embryo at stages of the developmental process. They are used to determine the types of cells that are developing in a certain region, as well as their location within that region. Fate map...
3g), with CD48−/lo MkPs being significantly closer to Sca-1lo HSCs in transcript space (Fig. 3h). To extract putative developmental trajectories between HSC and progenitor subpopulations, we applied the graph abstraction method PAGA47 (Fig. 3i). PAGA recovered the topology inferred from ...
The data provide an experimental verification of the morphological fate map of Poulson (1950) and a means of localizing gynandromorph maps to the blastoderm.doi:10.1016/0012-1606(80)90431-5E.M. UnderwoodProgram in Molecular, Cell and Developmental Biology, Department of Biology, Indiana ...
Fate maps are generated by marking and tracking cells in vivo to determine how progenitors contribute to specific structures and cell types in developing and adult tissue. An advance in this concept is Genetic Inducible Fate Mapping (GIFM), linking gene expression, cell fate, and cell behaviors ...
Our studies identify two regions in the early primitive streak, one which generates cells of the AHF and a second from which cardiac progenitors of the PHF and SHF emerge. References [1] Tam P, Schoenwolf G (1999) Cardiac fate maps: Lineage allocation, morphogenetic movement and cell ...