This chapter reviews the effect of old age on body fat distribution and on carbohydrate metabolism, especially insulin secretion and insulin action. Aging is associated with increased insulin resistance and risk for diabetes. One of the most important factors leading to insulin resistance in aging is...
WASHINGTON, June 14 (Xinhua) -- A study published on Thursday in the journal Cell Metabolism showed that the reward center of the brain valued foods high in both fat and carbohydrate more than foods containing only fat or only carbohydrate, lending a clue why modern people tend to gain weigh...
Tittgemeyer warned, however, that what may once have been a useful survival mechanism has now become a serious health risk to human societies which enjoyed an abundance of food, including naturally rare variants with high fat and carbohydrate levels. The result was a rapidly growing incidence of...
5a). Thus, NUC alters potential metabolic functions of gut microbiota mainly involving lipid and carbohydrate metabolism and glycan biosynthesis and metabolism. Fig. 5: Prediction of potential metabolic functions of gut microbiota and the effects of NUC on lipid metabolism gene expression and serum ...
Saturated fat intake was significantly lower in the intervention group than in the comparison group (means: 9.5% and 12.4%, respectively). Dietary polyunsaturated fat was also lower (difference = 1.5%), and dietary carbohydrate was higher (difference = 8.1%) in the intervention group than in ...
Nature Metabolism3,1342–1356 (2021)Cite this article 6701Accesses 162Altmetric Metrics Abstract Diet-induced obesity is a major risk factor for metabolic syndrome, diabetes and cardiovascular disease. Here, we show that a 5-d fasting-mimicking diet (FMD), administered every 4 weeks for a period...
Energy metabolism The tricarboxylic acid (TCA) cycle, the central hub connecting carbohydrate, fat and protein metabolism, is the main way that the body obtains energy and also provides raw materials for many biosynthesis processes in the body. The intake of a high-fat diet breaks the balance ...
Bedford and Classen, 1992 M.R. Bedford, H.L. Classen Reduction of intestinal viscosity through manipulation of dietary rye and pentosa-nase concentration is effected through changes in the carbohydrate composition of the intestinal aqueous phase and results in improved growth rate and food conversion...
The heart extracted considerable amounts of these non-carbohydrate foodstuffs. Myocardial extraction ratios of fatty acids were particularly great after a high fat intake, suggesting storage of fat in the heart muscle. A negative correlation between myocardial carbohydrate and ketone utilization was ...
Mechanistically, physical interaction between HSL, independent of lipase activity, and the isoform activated by glucose metabolism ChREBPα impairs ChREBPα translocation into the nucleus and induction of ChREBPβ, the isoform with high transcriptional activity that is strongly associated with whole-...