Rer1p binds to the same polar residues on the NCT TMD that are essential for interaction with APH1, and thus blocks APH1 interaction with NCT during the early stages of γ-secretase complex assembly. Hence, Rer1p controls formation of γ-secretase subcomplexes and, concomitantly, total ...
Physiotherapy, Department of Health Sciences, Lund University, Lund, Sweden Background: The purpose of this work was to study the performance and reliability of a test of fast alternating forearm movements and its relationship with measures of lower extremity function in older women with dementia. ...
Physiotherapy, Department of Health Sciences, Lund University, Lund, Sweden Background: The purpose of this work was to study the performance and reliability of a test of fast alternating forearm movements and its relationship with measures of lower extremity function in older women with dementia. ...
Indeed, the incoming stream of sensory signals in the CNS is encoded as trains of action potentials; processed in stages in the sequential relay nuclei of the spinal cord, brain stem, thalamus, and cerebral cortex; and modulated by superspinal centers through descending pathways, according to ...