The Family Heart Foundation is a patient-driven nonprofit organization focused on advocacy, research, and education in the healthcare sector, specifically addressing familial hypercholesterolemia and elevated Lipoprotein(a). Use the CB Insights Platform
Considerable preventive medicine and anticipatory guidance can be pro¬vided for the family of a woman found to have hyperlipidemia. Precise etiological diagnosis of her lipid disorder enables the physician to give diet¬ary advice and, when appropriate, genetic counseling. For the sake of this ...
CD36 endocytosis low-density lipoprotein metabolism Vav2 Atherosclerosis, a chronic inflammatory disorder involving macrophages, is the leading cause of cardiovascular diseases, which are projected to cause 23.6 million deaths by 2030 (1). A critical step of atherosclerosis lesion development is the accu...
Apolipoprotein A-I (Glu 198+Lys): A Mutant of the Major Apolipoprotein of High-Density Lipoproteins Occurring in a Family with Dyslipoproteinemia WOLFGANG STROBL, HANS-ULLRICH JABS, MICHAEL HAYDE, THERESIA HOLZINGER, GERD ASSMANN, AND KURT WIDHALM Department of Pediatrics, University of Vienna, ...
JADE: Joint Asia Diabetes Evaluation LDL-C: Low-density lipoprotein cholesterol SMBG: Self-monitoring of blood glucose References Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 ...
Another member of this family, PPARγ, functions as a receptor for oxidized metabolites of cholesteryl esters and regulates macrophage gene expression upon uptake of oxidized low density lipoprotein (LDL) (6, 7). However, the first protein characterized as oxysterol binding and hence named oxysterol...
The blood cell count was determined with a Coulter Hematology analyzer (Beckman–Coulter, Brea, CA). Fasting plasma glucose (FPG), HbA1c, insulin, total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, and liver markers serum levels were assayed. Serum insulin concentrations ...
The biochemical parameters, consisting of albumin (Alb), creatinine (Cr), uric acid (UA), fasting blood glucose (FBG), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), and high-density lipoprotein-cholesterol (HDL-C) levels, were evaluated by the Hitachi 912 automated ...
Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A<inf>2</inf> 2012, Journal of Lipid Research Citation Excerpt : Although it is clear that there is a positive association between Lp-PLA2 activity and CAD, the strength of this association app...
Subsequent to three weeks of weaning, all the offspring mice were transitioned to a high-fat diet. The levels of serum triglycerides (TGs), cholesterol (TC), low-density lipoprotein (LDL-C), total bile acid (TAB), non-esterified fatty acid (NEFA), and bile acids in mouse feces were ...