1) familial gastric cancer 家族性胃癌1. BACKGROUND&AIM: To detect the germline mutations in E-Cadherin gene(CDH1)and to investigate their possible role in familial gastric cancer. 背景与目的:检测E_Cadherin(CDH1)基因在家族性胃癌中的突变情况以探讨CDH1基因胚系突变在家族性胃癌中的作用。
Objective:The different germline mutations are known to cause breast cancer (BC), which might have induced as some other malignancies in degrees of relatives, and an increased risk of developing BC and clinical outcomes. Therefore we aim to investigate whether the independent familial gastric cancer...
In order to optimize the care and increase the knowledge on hereditary gastric cancer it is important to centralize medical care for these patients. National and international collaboration is warranted to improve the quality of research by increasing the size of study cohorts....
美 英 un.家族集团 网络家族聚集性;家庭聚集性;家族性聚集 英汉 网络释义 un. 1. 家族集团
cancer ncáncer m;bladder —cáncer vesical (form), cáncer de vejiga;bone —cáncer óseoorde hueso;breast —cáncer de mamaorpecho;cervical —cáncer cervical;colon —cáncer de colon;colorectal —cáncer colorrectal;esophageal —cáncer de esófago;gastric —cáncer gástricoorde estómago;head and...
Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study Bardram, Linda;Hansen, Thomas V. O.;Gerdes, AnneMarie;Timshel, Susanne;FriisHansen, Lennart;Federspiel, Birgitte 231-242 The MUTYH hotspot mutations p....
Pasanisi P,Bruno E,Venturelli E,et al.Serum levels ofIGF-I and BRCA penetrance:a case control study inbreast cancer families. Familial Cancer . 2011... Patrizia,Pasanisi,Eleonora,... - 《Familial Cancer》 被引量: 35发表: 2011年 Cancer in Families The contribution of low-penetrant suscepti...
that the relative risk (observed cancers over the number expected in the general population) in FAP was 331 for duodenal cancer and 124 for periampullary cancer. There was no excess risk for gastric cancer. However, it is interesting to note that in countries in which gastric cancer is...
1c). Strikingly, whole-exome sequencing analysis performed in a diagnostic context found a fourth family containing multiple papillary thyroid cancer patients (Fig. 1d). Also, in these two families no known pathogenic variants were identified in other cancer-associated genes. The TP53β-stop-lost...
Objective To report 7 patients with familial intestinal gastric cancer(FIGC) from 2 kindreds and analyze its clinical features. Methods Two kindreds of fam... Q Sun,WB Jin - 《Chinese Journal of Gastrointestinal Surgery》 被引量: 2发表: 2004年 "FAMILIAL LISSENCEPHALY"; CASE SERIES OF FIVE ...