FAM46C() 基因名: FAM46C 别名: 基因ID: 0 Chromosome:(GRCh37) Start: End: Strand: 信号通路: FAM46C 基因突变与药物关于我们 “基因医生”项目,可以为肿瘤患者提供全流程逐级的治疗方案与治疗手段。本项目创始科学家团队在基础医学研究领域拥有丰厚实战经验,以NGS及RNA-SEQ基因检测技术为基础,通过对...
Barbieri, M., et al., Compendium of FAM46C gene mutations in plasma cell dyscrasias. Br J Haematol, 2016. 174(4): p. 642-5.Barbieri M, Manzoni M, Fabris S, et al. Compendium of FAM46C gene mutations in plasma cell dyscrasias. Br J Haematol. 2016;174(4): 642-645....
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We construct the wild-type (WT) and mutant (MUT) type of the 3 ′ untranscriptional region (3 ′UTR) of FAM46C to the downstream of the firefly luciferase reporter gene of pGL3 vectors. The activity of the luciferase is detected using the dual luciferase reporter assay system (Promeg...
检测仪器:ABI Prism®7500/7900; Bio-Rad CFX 96; Rotor Gene™ 6000; Bio-Rad CFX96; SLAN; MIC POC Dx48 ; 规格:25 Test。 Protocol: 1. 符合相关规定的样品采集、储存和运输。 2. RNA提取。 3. 内部对照:1μl/T的量添加到提取混合物...
该研究采用农业水文生态系统模型(Agro-Hydrological & Chemical and Crop systems simulator, AHC)与基因表达式编程(Gene Expression Programming, GEP)相结合的方法构建作物水分生产函数。以河套灌区3种主要作物(葵花、玉米、小麦)为研究对象,采用AHC模型模...
Especially, macrophage-derived exosomes modulate the gene expression of cancer cells by delivering miRNAs to downregulate specific genes. FAM46C, also known as terminal nucleotidyltransferase 5C (TENT5C), is initially recognized as a non-canonical polyadenylate ribonucleic acid polymerase and has been...
Although FAM46C expression is down-modulated in several tumours, significant mutations in the FAM46C gene are only found in multiple myeloma (MM). Consequently, its tumour suppressor activity has primarily been studied in the MM context. However, emerging evidence suggests ...
Gene knockout of FAM46C in mice resulted in male sterility, characterized by the production of headless spermatozoa in testes. Sperm heads were intermittently found in the epididymides of FAM46C knockout mice, but their fertilization ability was severely compromised based on the results of ...
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