Mazzarella and colleagues8reported features suggestive of nuclear localization in the FAM50A amino acid sequence. cNLS mapper (http://nls-mapper.iab.keio.ac.jp/cgi-bin/NLS_Mapper_form.cgi) indicated that FAM50A (GenBank ID:NP_004690.1) contained a nuclear localization signal (NLS), ITTKKRKLG...
Here, we test 32.4 million sequence variants identified through whole-genome sequencing (WGS) of 15,220 Icelanders for association with diverticular disease (5,426 cases) and its more severe form diverticulitis (2,764 cases). Subsequently, 16 sequence variants are followed up in a diverticular ...
Its mature, circular form is shown in the lower part of the panel, and includes exons 2–6. Full size image Table 1 Top10 upregulated circRNAs in IDD samples. Full size table Circ-FAM169A is upregulated in degenerative NP tissues and regulates the synthesis of ECM components qRT-PCR ...
AstraZeneca in oncology AstraZeneca is leading a revolution in oncology with the ambition to provide cures for cancer in every form, following the science to understand cancer and all its complexities to discover, develop and del...
The taxonomic status of this form is still to be evaluated. Even though no cultivars are known from old garden literature, a few records of popular, rural knowledge can be found regarding different qualities of the species’ plant material. From the province of Blekinge, one of the several ...
ENHERTU has now been granted five Breakthrough Therapy Designations, including three in breast cancer and one in both lung and gastric cancers WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca and Daiichi Sankyo’s ENHERTU®(fam-trastuzumab deruxtecan-nxki)has been granted Breakthrough Therapy ...
. . 103 DocID13495 Rev 7 9/108 9 Description 1 STR91xFAxxx Description STR91xFA is a series of ARM®-powered microcontrollers which combines a 16/32-bit ARM966E-S RISC processor core, dual-bank Flash memory, large SRAM for data or code, and a rich peripheral set to form an ideal...
AstraZeneca is leading a revolution in oncology with the ambition to provide cures for cancer in every form, following the science to understand cancer and all its complexities to discover, develop and deliver life-changing medicines to patients. ...
According to the latest estimation of the International Diabetes Federation from 2021, approximately 537 million adults were living with diabetes and 541 million people were at increased risk of developing type 2 diabetes (T2D), the most common form [1]. Once insulin resistance has developed the ...
AstraZeneca is leading a revolution in oncology with the ambition to provide cures for cancer in every form, following the science to understand cancer and all its complexities to discover, develop and deliver life-changing medicines to patients. ...