Acute liver failure (ALF) is a life-threatening disease that occurs secondary to drug toxicity, infection or a devastating immune response. Orthotopic liver transplantation is an effective treatment but limited by the shortage of donor organs, the requir
Adult rat LC differentiation is believed to occur in four consecutive stages; stem cells that differentiate into spindle-shaped precursor Leydig cells (PLCs), round immature Leydig cells (ILCs), and polygonal mature ALCs. These forms were discovered in studies on rats [50,51,52] and similar ...