Intervention: Treatment with BAT and GDMT, or GDMT alonePrimary endpoint: 6MWT, NYHA functional class, NT-proBNP level, and QoL NA, 146 Phase II trial of BAT in HFrEF indicates that the procedure was safe with a pacemaker-like safety profile and a short learning curve. Of 146 patients, ...
use of medications and devices at baseline (diuretic, beta-blocker, digitalis, calcium channel blocker, nitrate, antiarrhythmic, antiplatelet, anticoagulant, and pacemaker), randomized treatment, stratification variable, and time to first occurrence of the composite outcome, worsening HF event, cardiovascul...
Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication. Flecainide intoxication is a severe intoxication that can lead to cardiogenic shock. We report on a 68-year-old female patient, who presented with a flecai... M Heldens,GVDVD Nat,P Melman - 《Netherlands...
16. The system of claim 10, wherein the control system is configured to obtain a blood pressure measurement. 17. The system of claim 2, further comprising a pacemaker configured to enforce a heart rate to meet metabolic demand. 18. The system of claim 2, wherein the short term changes ...
patients have a poor 5-year survival rate with an elevated risk of cardiovascular and heart failure admission3,4. Existing drugs may not effectively prevent disease progression in all patients. Ongoing research and development efforts aim to address the unmet needs in heart failure treatment and imp...
diabetes mellitus; autonomic neuropathy; limiting peripheral arterial disease; implanted pacemaker; treatment with b blockers; and atrial fibrillation. The local Tayside ethics and research committee approved the study before recruitment. All patients gave written and informed consent to participate in the...
treatment. Non-response occurs as a result of pre-implant, peri-implant and post implant factors but the technical constraints of traditional, transvenous epicardial CRT mean they can be challenging to overcome. In an effort to improve response, novel alternative methods of CRT delivery have been...
to stimulate the non-selective cationic current (If) which drives spontaneous depolarisation of pacemaker tissues such as the sinoatrial and atrioventricular nodes and purkinje fibres. The activation of the IKAChresults in membrane hyperpolarisation, increasing the cells threshold for firing which ...
HUMIR is a prospective registry designed to systematically gather comprehensive clinical data on consecutive patients who receive treatment for an acute myocardial infarction (AMI) event in Hungary. The data capture and follow-up procedures of the HUMIR have been extensively documented in previous ...
Control of pacemaker tissue, and thus, heart rate is provided predominantly by neurons of the nucleus ambiguus. Although most of the DVMN neurons innervate the visceral organs, a subpopulation of these cells with cardiac projections provides functional innervation of the LV and modulates its ...