Requirement already up-to-date: six in ./anaconda3/lib/python3.5/site-packages (from patsy->pyflux) Building wheels for collected packages: pyflux Running setup.py bdist_wheel for pyflux ... done Stored in directory: /Users/yuanlinwu/Library/Caches/pip/wheels/e8/fa/52/266ee11592454972ee33d4...