Type 2 diabetes (T2DFatty acidsDesaturasePolymorphism(sTo explore whether plasma fatty acids and SNPs in the fatty acid desaturase (FADS) gene associated with type 2 diabetes (T2D) and coronary artery disease (CAD). In this cross-sectional study, we utilized gas chromatography–mass spectrometric ...
The low D5D activity in serum lipids has been identified as a potential biomarker in the prediction of disease status, such as metabolic risk in children, hepatic steatosis, type 2 diabetes, and cancers [3,11–13]. A recent The Cancer Genome Atlas (TCGA) database analysis has indicated ...
Type 2 diabetes mellitus (T2DM) is a global public health problem often associated with obesity. Bariatric surgery is effective for treating serious obesity, and techniques involving intestinal bypass have metabolic benefits, such as complete and early remission of T2DM. We present a literature review...
A recently candidate-wide association study (CWAS) detected SNPs in susceptibility loci of several traits such as lipid levels, type 2 diabetes and obesity in PCOS cases. None of the metabolic-related SNPs was asso- ciated with PCOS after strict correction for multiple testing40. The mixed ...
Objective Human genetic variants near the FADS (fatty acid desaturase) gene cluster (FADS1-2-3) are strongly associated with cardiometabolic traits including dyslipidemia, fatty liver, type 2 diabetes mellitus, and coronary artery disease. However, mechanisms underlying these genetic associations are ...
Polymorphism of rs174616 in the FADS1-FADS2 gene cluster is associated with a reduced risk of type 2 diabetes mellitus in northern Han Chinese people. Diabetes Res. Clin. Pract. 2015, 109, 206-212. [CrossRef] [PubMed]Polymorphisms of rs174616 in the FADS1-FADS2 gene cluster is ...