Affinity probing of flavin binding sites. 1. Covalent attachment of 8-(methylsulfonyl)FAD to pig...Examines the reaction of 8-(Methylsulfonyl)FAD with single cysteine residue (Cys449) in pig apolipoamide dehydrogenase to generate a flavinated enzyme containing covalently-bound 8-(cystenyl)FAD ...
Interestingly, the mutant generated by changing the first glycine of the proposed FAD-binding domain (GxGxxG) to alanine revealed catalytic activities, but was lower than those seen with the unmodified form. The conversion of the first glycine to alanine markedly increased and decreased the K m ...
FAD2 performance locus and corresponding target site-specific binding protein capable of inducing targeted cleavageA method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 ...
ThermoFAD, a Thermofluor®-adapted flavin ad hoc detection system for protein folding and ligand binding. FEBS J. 2009; 3 :2833–2840. doi: 10.1111/j.1742-4658.2009.07006.x. [ Cross Ref ]Forneris F, Orru R, Bonivento D et al (2009) FEBS J 276:2833–2840...
Effect of the myeloperoxidase inhibitor AZD3241 on translocator protein binding in brain—A positron emission tomography study in patients with Parkinson’s disease. Mov Disord. 2014; 29 :S662.Jucaite A, Svenningsson P, Rinne J, Cselenyi Z, Varrone A, Karlsson P, Varna¨s K, Johnstro¨m...
And method of producing such molecules, and also features prophylactic use and / or their therapeutic.モハメド,ネハルスパイタルニー,ジョージ,エルキャセイ,レスリー,エスジョンズ,スティーブン,マリオンパンクス,スティーブン イー....
Structure, dynamics and binding of drug resistance HIV-1 protease with major mutationsOrnjira Aruksakunwong