Each POU domain can bind a sequence of four base pairs in the major groove of the cognate DNA sequence, thereby placing each POU domain on either side of the DNA helix and effectively encircling target DNA sequ
With statistical modelling of the twin data, we show that both these relationships are partly due to pleiotropic genetic influences common to each trait. We also find a trend for heterosexuals with a nonheterosexual twin to have more opposite-sex partners than do heterosexual twin pairs. Taken ...
In this study, we show that automated NEI and machine learning can be used for the detection of EVs secreted byMtb-infected cells (MtbEVs), by leveraging the surface expression of factors abundantly expressed on theMtbmembrane. The NEI used in this study targeted the glycolipid lipoarabinomannan...
The former comprises of two strongly related pairs: {POC, Chla} and {DOC, pH}, while the latter contains one such pair: {Feo, Temp}. The composition of the first cluster and connection between the first two pairs have already been explained (Section 3.1.1). Dzierzbicka-Glowacka et ...
pairs of features had correlation coefficients greater than 0.8, no features were removed at this stage. To further reduce model complexity and mitigate the risk of overfitting, LASSO analysis with five rounds of tenfold cross-validation was applied to eliminate highly correlated features, as ...
This initial step allowed us to identify pairs of variables that were highly correlated and could potentially lead to multicollinearity issues. We further quantified the degree of multicollinearity using variance inflation factors (VIF) for each predictor variable (Daoud 2017). The VIF values provided ...
CAP and LTS encompass both adopted and non-adopted sibling pairs as well as same-sex twin pairs. The CATSLife1 sample includes 1,327 individuals ranging from 28 to 51 years (Mage = 33.45 years,SD = 5.04, 53.1% female). The majority of participants were White (92.2%) and non...
The efficiencies of PCR with the 5 primer pairs did not differ substantially (Table 3), minimizing any additional effect of PCR effi- ciency on the area of the melting peaks. Quantification of genes encoding ETEC fimbriae by multiplex HRM-qPCR To establish calibration curves for individual ...
oxidant4,35, and no T based lesion has been specifically identified. The sequences flanking 1 bp T deletions displayed a random distribution of C:G and A:T base pairs, indicating that the T deletions were unlikely to be collateral mutations caused by extended synthesis via deletion-prone...
A total of 73 homologous gene groups were obtained by OrthoMCL software, containing 543 paralogous, 452 orthologous, and 677 coortholo- gous gene pairs. Results of the comparison between different species are presented in Table 2. A large number of Scientific Reports | 6:23101 | DOI: ...