Cardiovascular disease (CVD) remains a leading cause of death worldwide, but age-standardized CVD death rates are decreasing steadily. In this Review, Ezzati and colleagues use the available epidemiological data to examine regional and global changes in
This observation suggests that SDI significantly modified the effects of clinical risk factors and demographic variables on youth SI (\({\chi }^{2}(72)\)=98.55, p = 0.02 for Model 4 vs. Model 3). The following interactions were significant in the final model (i.e., Model 4): ...
383–4072 (3%) experienced overdose. Twenty-one (81%) studies were conducted in North America and 23 (89%) reported polydrug use. Psychosocial factors associated with risk of overdose (n = 103) were identified and thematically organised into ten groups. These were: income; housing instabi...
In contrast to traditional perspectives of resilience as a stable, trait-like characteristic, resilience is now recognized as a multidimentional, dynamic capacity influenced by life-long interactions between internal and environmental resources. We review psychosocial and neurobiological factors associated with...
Diabetic nephropathy (DN) affects about 40% of diabetes mellitus (DM) patients and is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) all over the world, especially in high- and middle-income countries. Most DN has be
Numerous molecular factors orchestrate the development of the peripheral taste system. The unique anatomy/function of the taste system makes this system ideal for understanding the mechanisms by which these factors function; yet the taste system is under
In this study, Global Burden of Disease investigators characterize trends in mortality, life expectancy, and prevalence associated with most common
It has been previously shown that heme oxygenase-1(HMOX1) is modulated by MAFK [31], and a recent proteomics study found that MATIIA is recruited to the HMOX1 gene locus in X63/0 and Hepa1 cells and revealed a physical interaction between MAFK and MATIIA. The knockdown of MATIIA ...
A total of 156 factors associated with depression were identified which were clustered into somatic, psychological, social and sociodemographic factors. Pre-existing depression and personality factors were the most consistent associated factors with depression in cancer patients, while for most somatic and...
K. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007–2008 Arthritis Rheum. 63, 3136–3141 (2011). PubMed Google Scholar Badley E. D. M. Arthritis in Canada: an ongoing challenge (Health Canada, Ottawa, 2003). ...