CoV-2 infection, and find that this antiviral activity extends to diverse respiratory viruses. Taken together, our bidirectional CRISPR screens dissect the densely interconnected landscape of proviral and antiviral host factors, highlighting mucins as potential restriction factors of SARS-CoV-2 infection....
Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CRISPR dropout
The median age at repair was 8 months (range, 36 days–18.5 months) with a median weight of 7.2 kg (range, 2.8-12). The spectrum of age ranges were less than 3 months (n = 12), 3 to less than 6 months (n = 20), 6 to less than 9 months (n = 21), and older than 9 ...
Meaning Findings of this study suggest that racial differences in cardiovascular health are attenuated by varying experiences with neighborhood physical and social environments as well as by lived personal experiences with discrimination; approaches to improve ICH that target neighborhood factors and discrimina...
As a result, a range of methods have been developed to specifically measure this concept, including the Driver Behaviour Questionnaire [3] and the Wiener Fahrprobe method [4]. Estimates suggest that driving error is a causal factor in 75% [5], and in some cases even up to 95% [6] of...
Meta-regression analyses showed that female sex, older age, and higher BMI (all p < 0.01) are associated with higher prevalence rates of SRDE. Conclusion The outcome of this review suggests that factors specific to the sport affect eating behaviors throughout an athlete's life. As a ...
that “disordered eating” (defined and discussed below) is qualitatively different from the eating disorders [10,11,12]. For this reason, screening tests aimed at measuring patterns of disordered eating are thought not to be a good proxy for estimating the prevalence of eating disorders based ...
Avian pathogenic Escherichia coli (APEC) is the principle cause of colibacillosis affecting poultry. The main challenge to the poultry industry is antimicrobial resistance and the emergence of multidrug resistant bacteria that threaten the safety of the food chain. Risk factors associated with emergence...
The global spread of SARS-CoV-2 is posing major public health challenges. One feature of SARS-CoV-2 spike protein is the insertion of multi-basic residues at the S1/S2 subunit cleavage site. Here, we find that the virus with intact spike (Sfull) preferen
As China has entered a new stage of high-quality development, clarifying the mechanism and spatial characteristics of green development for urban agglomerations are critical to sustainable development. Based on the data of 11 major cities in the Harbin-C