A study was carried out to evaluate some parameters which may have an effect on the dissolution rate of prednisone from tablets. The parameters examined involving formulation were: diluent proportion (Lactose-starch), dissintegrant type (starch, explotab (sodium starch glycolate) type of binder (...
an official disintegration test. Solid drug products exempted from disintegration tests include troches, tablets which are intended to be chewed, and drug products intended to sustained release or prolonged or repeat action. The process of disintegration does not imply complete dissolution of the ...
The effects of the magnesium stearate, talc and gelatin contents of spironolactone tablets on dissolution rate and bioavailability of the drug have been evaluated. The dissolution test results for eight formulations corresponding to a 2脳2脳2 factorial design showed dissolution rates to be chiefly ...
A study of the influence of formulation factors and processing techniques on the dissolution rates of hydrochlorothiazide tablets 来自 Semantic Scholar 喜欢 0 阅读量: 21 作者: P Seth 摘要: Contact angles of pharmaceutical powders were determined by measuring the maximum height of a drop of a ...
Also the properties of interest (chemical stability, dissolution rate of the fibres) are selected based on fixed points of viscosity, both in terms of ... D Radu,V Dima,M Eftimie 被引量: 0发表: 2010年 加载更多研究点推荐 Sustained release tablets plastic matrix type ...
of 2.5%w/w and 10%w/w in chloroquine phosphate tablet formulations.The mechanical properties of the tablets,measured by the tensile strength(T) and brittle fracture index(BFI) as well as the release properties measured by the disintegration time(DT) and dissolution time(t80- time for 80%...
Through improved formulation, the controlled release of drugs from the nasal cavity to the brain will be possible. For example, it has been reported that polymers such as pluronic F-127 had a controlled release mechanism through the dissolution and diffusion of drugs depending upon their concentrati...
Jacob, J. T., Plein, E. M. (1968). Factors affecting dissolution rate of medicaments from tablets II: Effect of binder concentration, tablet hardness, and storage conditions on the dissolution rate of phenobarbital from tablets, J. Pharm. Sci. 57: 802 - 805....
Factors affecting the disintegration and dissolution of chloroquine phosphate/ starch tablets. J. Pharm. Pharmacol. 30, 214-219.Pilpel N,Otuyemi SO,Kurup TRR.Factors affecting the disintegration and dissolution of chloroquine phosphate/ starch tablets. Journal of Pharmaceutical Sciences . 1978...
Jacob, J. T., Plein, E. M. (1968). Factors affecting dissolution rate of medicaments from tablets II: Effect of binder concentration, tablet hardness, and storage conditions on the dissolution rate of phenobarbital from tablets, J. Pharm. Sci. 57: 802 - 805....