and S.P. Bajaj, Structure-function relationships in factor IX and factor IXa. Trends Cardiovasc Med, 2003. 13(1): p. 39-45.Schmidt AE, Bajaj SP. Structure-function relationships in factor IX and factor IXa. Tre
Factor XII (FXII), the precursor of the protease FXIIa, contributes to pathologic processes including angioedema and thrombosis. Here, we review recent work on structure-function relationships for FXII based on studies using recombinant FXII variants. Author...
This end-point depends on: 1) the concentrations and activities of contact factorsprekallikrein, high-molecular-weight kininogen (HMWK) andfactor XII; 2) the concentrations and activities ofcoagulation factors XI, IX, VIII, X, V, II and fibrinogen; and 3) the sensitivity of the whole test ...
there are numerous contradictory reports about the synthesis and presentation of TF on blood cells and circulation in normal blood either on microparticles or as a soluble protein. Another subject of controversy is related to the structure/function of TF. It has been almost commonly accepted that ...
The factor structure of the BRIEF-A was examined via a confirmatory factor analysis. We also evaluated whether BRIEF-A scores differed among university students varying in severity of depressive symptoms (Minimal, Mild, Moderate, Severe) as measured by the Beck Depression Inventory – II. Results ...
DNA-binding domains of plant-specific transcription factors: structure, function, and evolution. Trends Plant Sci 18, 267–276 (2013). Article CAS PubMed Google Scholar Atchley, W. R., Terhalle, W. & Dress, A. Positional dependence, cliques, and predictive motifs in the bHLH protein domai...
In addition to conserved protein domains, the pattern of intron positions between ARF subgroups can also provide some clues on evolutionary relationships. To identify the introns-exons structure of individual StARF member, a comparison of the full-length cDNA sequences with the corresponding genomic ...
Phylogenetic relationships, gene structure and motif compositons ofPopulusNAC genes.A. Multiple alignments of 163 full-length amino acids of NAC genes fromPopuluswere executed by Clustal X 1.83 and the phylogenetic tree was constructed using MEGA 4.0 by the Neighbor-Joining (NJ) method with 1,000...
Figure 5. Structure–function relationships of rFasxiator. (A) Sequence alignment of two FXIa‐specific Kunitz‐type inhibitors. Yellow color: identical residues; green color: conserved residues. To increase potency and selectivity of rFasxiator, we selected residues (identified by arrowheads) that...
FH = Complement factor H, FI = Complement factor I, AP = alternative pathway, VWF = von Willebrand factor, aPTT = activated partial thromboplastin time, TM = Thrombomodulin, FIIa = thrombin, FXI = factor XI, FXII = factor XII, FXIII = factor...