Safety and efficacy of repeat doses of factor Xa (recombinant), inactivated-zhzo not established.Interference with Effects of HeparinMay interfere with the anticoagulant effect of heparin. (See Specific Drugs under Interactions.)ImmunogenicityPotential for immunogenicity with use of all therapeutic ...
& Esmon, C.T. (1979) Interaction between heparin and factor Xa inhibi- tion of prothrombin activation. Biochim. biophys. Acta, 585, 405-415.Walker FJ, Esmon CT: Interactions between heparin and factor Xa: Inhibition of prothrombin activation. Biochim Biophys Acta 585:405, 1979...
Safety, pharmacokinetics and pharmacodynamics of single doses of rivaroxaban - an oral, direct factor Xa inhibitor - in elderly Chinese subjects. Rivaroxaban is a novel, oral, direct factor Xa (FXa) inhibitor for the prevention and treatment of thromboembolic disorders. The aim of this study was...
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This study investigated the safety, pharmacokinetics and pharmacodynamics of multiple oral doses of R1663, a factor Xa inhibitor, and explored the influence of age and gender on pharmacokinetics and pharmacodynamics of R1663. This was a single-blind, randomised, placebo-controlled, dose escalation st...
(1) vesicle enumeration using nanoparticle tracking assay, imaging flow cytometry, and TF immunofluorescence localization in a single-vesicle analysis using microarrays; (2) cellular origin; and (3) TF-dependent Xa generation capacity, as well as assessing the contribution of the TF inhibitor, TFPI...
Thus, it is likely that these sex differences in the healthy and diseased brain result from complex interactions between sex hormones, BsreaxincShcri.o2m018o,s8o, m154es and epigenetic factors. 2 of 27 In view of these findings, increasing our understanding regarding the molecular basis of ...
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Combination therapies that incorporate HIF-1 inhibitors with other cancer therapies have considerable potential to improve treatment efficacy, ameliorate side effects, and reduce drug doses [16]. In the next section, we reviewed current research on the synergistic effects of HIF-1 inhibitors with diff...
Antifactor Xa activity in intensive care patients receiving thromboembolic prophylaxis with standard doses of enoxaparin. Thromb Res. 2002; 105 :201–204. doi: 10.1016/S0049-3848(02)00028-2. [ Cross Ref ]Mayr AJ, Dünser M, Jochberger S, Fries D, Klingler A, Joannidis M, Hasibeder W...