Elevation of factor VIII in acute liver necrosis. Influence of plasmapheresis. Digestion. 1973;8:360-367.BAELE, G. , VERMEIRE, P. , DEMEULENAERE, L. & BARBIER, F. ( 1973 ) Elevation of factor VIII in acute liver necrosis: influence of plasma pheresis . Digestion , 8 , 360 ....
Therefore, it is not surprising that chronic elevation of some coagulation factors has been associated with an increased risk of venous thrombosis. The strongest association has been between chronic elevated factors VIII, IX, XI, and prothrombin with venous thrombosis. There is currently no known ...
In contrast to the active site-blockers, protein C, a serine proteinase, degrades factor Va and VIIIa after its activation by thrombin in complex with protein S and thrombomodulin, a membrane protein on endothelial cells (Cramer et al., 2010; Gale, 2011). Fibrinolysis comprises a cascade ...
Following activation, the single-chain FIX becomes a 2-chain molecule, in which the 2 chains are linked by a disulfide bond attaching the enzyme to the Gla domain. Activated factor VIII (FVIIIa) is the specific cofactor for the full expression of FIXa activity. Platelets not only provide th...
[摘要] 血管性血友病因子在止血和血栓形成过程中起重要作用,vWF缺陷将导致血管性血友病,而在血栓性血小板减少性紫癜、冠心病、肿瘤的浸润与转移及糖尿病肾病等疾病,其活性水平可明显增高。现就血浆vWF活性水平与上述疾病关系的研究进展作一综述。 关键词: 血管性血友病因子 血管性血友病 血栓性疾病 ...
The primary adverse event was an elevation in the serum alanine aminotransferase level to 1.5 times the upper limit of the normal range or less. Progression of preexisting chronic arthropathy in one participant was the only serious adverse event. No neutralizing antibodies to factor VIII were ...
Elevation of Factor VIII Coagulant Activity Over Factor VIII Coagulant Antigen in Diabetic Children Without Vascular Disease: A Sign of Activation of the F... To investigate whether the elevation of factor VIII coagulant activity observed in children with poor control of diabetes is due to increased...
Plasma vWF regulates hemostasis by facilitating platelet adhesion and coagulation factor VIII (FVIII) stabilization29,30. Subendothelial vWF mediates initial attachment of platelet to the basement membrane after EC injury31. Deficiency of vWF, either quantitative or qualitative, causes a bleeding disorder...
Elevated factor VIII plasma levelsBackgroundCerebral venous thrombosis (CVT) is a potentially life-threatening condition that requires acute recognition and treatment. Diagnosis of CVT is challenging and requires a high index of clinical suspicion. The finding of the "cord sign" in a non-contrast ...
Strauss , H.S. et al. Elevation of Factor VIII (Antihemophilic Factor) During Pregnancy in Normal Persons and in a Patient with von Willebrand's Disease New Eng. J. Med. 269:1251-52 (1963). ;. 269:1251-52 (1963). Turrentine, M.A. et al. “Plasma from Donor Dogs, Pretreated wit...