Further analysis revealed that the activities of factor IX (FIX), factor XI (FXI) and FXII were significantly boosted, whereas that of factor VIII (FVIII) was depleted from the plasma on glass incubation. However, the activities of FIX, FXI and FXII were only slightly attenuated in SPI-...
the slight prolongation of aPTT29. Further analysis revealed that the activities of factor IX (FIX), factor XI (FXI) and FXII were significantly boosted, whereas that of factor VIII (FVIII) was depleted from the plasma on glass incubation. However, the activities of FIX, FXI and FXII were...
4C). Furthermore, PI3K-inhibitor (LY2940032) and Akt1/2-inhibitor (Akt VIII) prevented the ability of IGF-1 to increase LARP6 and pro-α1(I) expression (Fig. 4D). To further assess potential involvement of Akt, we overexpressed a constitutively active form of Akt1 (35) and Akt2 (36...
TUBB8 Tubulin β 8 class VIII Hit 9 0 0 a High-confidence LRIG1-interacting proteins according to Ref. 20 and 21 data sets were retrieved from the BioGrid portal (https://thebiogrid.org,3 May 4, 2017). b Total number of specific interactions of the respective bait in Refs. 20 and...
4.8. Factor VIII Activity Assays APTT clotting assays and video microscopy of clot growth assays were performed as described [34]. CS assays were performed with Coatest SP4 Factor VIII kit (Chromogenix; Diapharma, West Chester, OH, USA). An in-house FVIII standard was used as a calibrator....
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