Key Words: Factor V Leiden, thrombophilia, APC resistance, venous thrombosis, anticoagulation Venous thromboembolism (VTE; deep venous thrombosis [DVT] and/or pulmonary embolism) is a major medical problem, which affects approximately 1 in 1000 persons per year. VTE is a multicausal disease that ...
factor V Lei·den -ˈlī-dᵊn 1 : a point mutation producing an abnormal version of factor V that is resistant to inactivation and causes prolonged clotting of blood 2 also factor V Leiden thrombophilia : a genetic disorder caused by factor V Leiden that is marked by an ...
Factor V Leiden thrombophilia. GENEReviews, 1999. http://www. ncbi.nlm.nih.gov/bookshelf/br.fcgi?book_gene∂_factor-v-leiden. Accessed 3 June 2009.Kalafatis M,Mann KG.Factor V Leiden and thrombophilia. Arteriosclerosis Thrombosis and Vascular Biology . 1997...
Thrombophilia in infancy: factor V Leiden and MTHFR or factor II double heterozygocity as a risk factor. Pediatr Hematol Oncol 2003;20:219-27.Koren A, Levin C, Hujirat Y, El-Hasid R, Kutai M, Lanir N, Shalev S, Brenner B (2003) Thrombophilia in infancy: factor V Leiden and MTHFR...
Factor V LeidenFVLProthrombinThrombophiliaWe report an 81-year-old female with a heterozygous factor V Leiden mutation who developed purpura fulminans. Digital necrosis, a characteristic clinical feature of purpura fulminans was prominent. Purpura fulminans is more common in children and adult cases are...
ThrombophiliaFactor V LeidenProthrombin G20210AMTHFR C677T and A1298CObjective: The present case-control study aimed at evaluating the contribution of thrombophilic polymorphisms to acute venous (VTE) as well as arterial thrombotic events (ATE) in a population of young women with few traditional ...
Inappropriate Testing and Treatment of Factor V Leiden and Other Heritable ThrombophiliasScott J. Parsons DO aSven R. Olson MD bThomas G. DeLoughery MD, MACP, FAWM bThe American Journal of Medicine
Factor V Leiden and prothrombin G20210A mutations in pregnancies with adverse outcome Background: Inherited thrombophilia has been associated with obstetric complications through mechanisms that are not yet fully elucidated. The aim of this ... T Agorastos,A Karavida,A Lambropoulos,... - Journal...
Factor V Leiden, protein C, and lipoprotein (a) in catheter-related thrombosis in childhood: A prospective study To determine the association between catheter-related thromboses and hereditary causes of thrombophilia, including the factor V Leiden mutation, deficienci... Ulrike Nowak-G?ttl,A Dübber...
factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and ...