Acquired factor V deficiency is a rare condition associated with a wide variety of causes. We herein report the case of a 75-year-old man who developed acquired factor V deficiency associated with gastrointestinal bleeding after transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma...
Isolated reduction in factor V activity either occur in form of a hereditary deficiency of factor V as an acquired inhibitor against factor V. Diagnosis can not be made by bleeding alone because in both cases it can occur or not occur. Two patients were investigated showing pathological screening...
Zinc deficiency causes growth retardation and... Zeynep,Siklar,Ceyda,... - 《Journal of Tropical Pediatrics》 被引量: 31发表: 2003年 Genetic Description of Factor XI Deficiency in Holstein Semen in Western Japan Factor XI deficiency was detected in Holstein cows and mummified foetuses in Japan;...
Twitter Google Share on Facebook (redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
Mutations in LMAN1 (ERGIC-53) or MCFD2 cause combined deficiency of factor V and factor VIII (F5F8D). LMAN1 and MCFD2 form a protein complex that functions as a cargo receptor ferrying FV and FVIII from the endoplasmic reticulum to the Golgi. In this study, we analyzed 10 previously ...
A 12-year-old previously healthy male, with a family history of protein S deficiency, presented with confusion, aphasia, and right upper extremity weakness after a 10-day febrile illness. Imaging studies revealed sinovenous thrombosis and left parietal hemorrhagic stroke. On further investigation he...
FXII-, FXI-, FVIII-, FIX-, and PK-deficient plasmas from individuals with congenital factor deficiency were obtained from George King Bio-medical and had no detectable antigen level by western blotting and did not exhibit coagulant activity for each respective protein. FXII-deficient plasma ...
A proband's thrombophilia was considered idiopathic if all known (during the recruitment period of 1995–1997) biological causes (e.g., antithrombin deficiency, protein S and C deficiencies, activated protein C resistance, plasminogen deficiency, heparin cofactor II deficiency, Leiden factor V, dys...
The prevalence of ICH is highly variable among congenital bleeding disorders, with the highest incidence observed in factor (F) XIII deficiency (FXIIID) (30%). This life-threatening presentation is less common in afibrinogenemia, FVIII, FIX, FVII, and FX deficiencies, and is rare in severe ...
Individuals with a positive screening assay should have the DNA test for confirmation and to distinguish heterozygotes, homozygotes, and "pseudohomozygotes" who are heterozygous for both Factor V Leiden and a second mutation causing Factor V deficiency. When relatives of individuals known to have ...