In (3), introduce f(u;\lambda ) and g(x;\mu _j) as the probability mass functions of U and the X_j respectively. We have a set of observation pairs (y_{11},y_{12}),\ldots ,(y_{n1},y_{n2}). Since Y_1 and Y_2 are conditionally independent given U, the likelihood is...
et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor OCT4. Cell 95, 379–391 (1998). Article CAS PubMed Google Scholar Jolma, A. et al. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527, ...
The human fibroblast growth factor receptor (FGFR) family, a subfamily of receptor tyrosine kinases (RTKs), comprises of four family members—FGFR1, FGFR2, FGFR3 and FGFR4. A closely-related receptor which lacks the FGF signaling tyrosine kinase domain, FGFR5, (also known as FGFRL1) was re...
The results obtained show that expression of the gene is low at 23 degrees C and is induced rapidly at 37 degrees C. By deletion analysis, a promoter element necessary for high level induction by heat shock was located between base pairs -340 and -364 upstream of the translation start ...
Osteoarthritis (OA) is a painful, incurable disease affecting over 500 million people. Recent clinical trials of the nerve growth factor (NGF) inhibitors in OA patients have suggested adverse effects of NGF inhibition on joint structure. Here we report t
The sequences were compared in individual pairs using BESTFIT. For the receptors, the regions compared were those defined in Table 1. For the ligands, the regions compared were the entire region C-terminal to the membrane spanning sequence. The values given are percent amino acid identity, allo...
of common polymorphisms of the lipoprotein lipase and pon1 genes with the metabolic syndrome in a sample of community participantsGenomics, proteomics, metabolomics, lipidomics and glycomics405Gene expression quantification using multiplexed color-coded probe pairs to determine RNA content in sporadic ...
www.oiforum.com 43 OIF-ELSFP-01.0 4.3 Electrical Requirements Power for the ELSFP shall be delivered by six pairs of 3.3V power and ground pins. The current capability of each of these pins is up to 1.5 A DC with a maximum operating rating voltage of 30 V DC . The total module ...
(right) showing the differences between pairs of ORCA segments of population-median distances of REF and ALT alleles. P indicatesp-value from a two-sided binomial test.hPolymer reconstruction of the LCLAXIN2VCM 3D architecture obtained by ORCA from one representative LCL single cell for the REF...
Since a single response may contain multiple topics in the obtained free-associative descriptions, a list of biterms (pairs of two words that co-occur in documents) within a three-word distance (the minimum unit to describe co-occurrence relationships between words) was created. After that, we...