1b). This resulted in a library of 209,440 sequences. Fig. 1: Homotypic TFBS orientation effects on cis-regulatory activity. a, Schematic of MPRA library design and workflow. Eighteen TFBSs, homotypic and heterotypic singlets, pairs and triplets were tested in all possible orientations and ...
These four models were hierarchical and the adjacent pairs were statistically compared to examine the measurement invariance. Fourth, the measurement invariance over time and longitudinal cross-gender invariance was examined. The former used the guidelines by Liu et al. [53], while the latter used ...
Colgan (University of Colorado Denver), M. Tessier-Lavigne (Genentech) and C. Ledent (Université Libre de Bruxelles) for breeding pairs of gene-targeted mice. Supported by the University of Tübingen (Fortüne grants 1639-0-0 to P.R. and 1778-0-0 to V.M.), Deutsche Forschungs...
PCR was performed by amplifying 1 μL cDNA at 94°C for 1 minute, annealing for 1 minute, and 72°C for 1 minute for 40 cycles on a Perkin Elmer 9600 thermocycler (PE Applied Biosystems) using the following PlGF primer pairs: forward primer 5′-ACAAGCTTCCTACGTGGAGCTGACGTTCT-3′ and...
Quantification of symmetric and asymmetric divisions in cultures from 3-month-old (H) mice, Nrf2-/- NSPCs infected with control or NRF2ΔETGE expression lentivirus (I) and Nrf2+/+ NSPCs infected with control or shRNA lentivirus to knock-down NRF2 (J) (n = 60 pairs). Data show mean ...
2. Data correlation The systems ammonia + water (NH + HO) and water + lithium bromide (HO + LiBr) provide two working pairs most often used today in air-conditioning systems a... R Peters,C Korinth,JU Keller - 《Journal of Chemical & Engineering Data》 被引量: 31发表: 1995年...
and population size and structure are taken to be constant. In our approach, the correction factors,Z, were obtained after a spectral decomposition of the Brownian covariance matrix,C, defined as\({c}_{ij}=\min ({t}_{i},{t}_{j})\), for all pairs of individualsiandjand their corres...
Recent studies have elucidated cell-lineage-specific three-dimensional genome organization; however, how such specific architecture is established or maintained is unclear. We hypothesized that lineage-defining transcription factors maintain cell identity via global control of genome organization. These factors...
The results are presented as the mean ± SEM of n = 6 pairs of donors. The differences between control PMN and G-CSF PMN were statistically significant (P < .05). Download: Download full-size image Fig 6. Selective ADCC of PMN via FcγRI. Bispecific antibody 520C9 × 22 [F(ab')...
A recurrent theme of tryptophan-mediated and charge–charge interactions underscores the question of how cognate UHM–ULM pairs are determined. Although we show that the Tat-SF1 UHM is required for detectable SF3b1 association, it remains likely that auxiliary interfaces mediated by distinct protein ...