Transcription factors (TFs) play key roles in the regulation of gene expression by binding in a sequence-specific manner to genomic DNA. In eukaryotes, DNA binding is achieved by a wide range of structural forms and motifs. TFs are typically classified b
For each such value of R*BP compute ξ0 from Eq. (149) and ReBP from Eqs. (147) and (148). 6. From the computed value of ReBP and the assumed value of R*BP compute f′ from Eq. (138). 7. Repeat steps 4–6 as many times as desired and plot the pairs of points f′, ...
“High stringency conditions” for the annealing process may involve, for example, high temperature and/or low salt content, which disfavor hydrogen bonding contacts among mismatched base pairs. “Low stringency conditions” would involve lower temperature, and/or higher salt concentration than that ...
GW computes RIDiold=EKG(IDiold) for verifying the identity of MNi and then searches a pair (RIDiold,MIDiold) in the database to find a registered user. If the pairs (RIDi, MIDi) and (RIDiold,MIDiold) are equal, GW generates new random numbers rDnew and rGUnew, computes PIDinew=EKG...
The human fibroblast growth factor receptor (FGFR) family, a subfamily of receptor tyrosine kinases (RTKs), comprises of four family members—FGFR1, FGFR2, FGFR3 and FGFR4. A closely-related receptor which lacks the FGF signaling tyrosine kinase domain, FGFR5, (also known as FGFRL1) was re...
Poor expression yields of recombinant human factor IX are attributable to aberrant splicing in heterologous expression systems such as transgenic hosts for example, transgenic nonhuman mammal The aber
These two pairs of Raman lasers are right- and left-handed circularly polarized, respectively, and are assumed to co-propagate along the direction of the magnetic field. Moreover, the cavity field is linearly polarized along the y axis, which is per- pendicular to the magnetic field. The ...
To explore the prognostic related factors and mechanisms of gastric cancer (GC), we performed the systematic analysis with integrated bioinformatics tools based on multiple on-line datasets. With uni-variate COX analysis, we screened out 37 survival hazardous genes in GC. Further GO assays disclosed...
et al. Journal of Molecular Biology . 1999Grove A, Kassavetis GA, Johnson TE & Geiduschek EP (1999) The RNA polymerase III-recruiting factor TFIIIB induces a DNA bend between the TATA box and the transcriptional start site. J Mol Biol 285, 1429-1440....
To investigate the calcium ions adsorption kinetics in calcium ions solution, 20 mL calcium ions solution (2 mM) was incubated with 20 mg MS@D-HMP at 37 °C for a certain time (5, 15, 30, 60, 240, 480, 1440 min). Atomic absorption spectrophotometer (SPCA-626D, Shimadzu,...