The loxF8 site has 6 asymmetric positions and is located between base pairs 76-109 in the int1h regions (Fig. 1a). Fig. 1: Directed evolution of site-specific recombinases for the loxF8 target site. a Overview of the target site identification in the inverted repeats (int1h) surrounding...
1A, B). In addition to the FXII Thr309 missense mutations, HAE has been associated with either a F12 exon 9 deletion (c.971_1018 + 24del72*)54 or a duplication of 18 base pairs (c.892_909dup) that lead to loss of amino acids Lys305-Ala321 or repetition of amino acids (...
6). Indeed, hundreds of TF pairs are significantly enriched for common ASBs (one-tailed Fisher’s exact test P value from 0.05 to 10−300 upon correction for multiple tested TF pairs with the Benjamini–Hochberg procedure). As a rule, shared ASBs were not related to interacting TFs (...
These four models were hierarchical and the adjacent pairs were statistically compared to examine the measurement invariance. Fourth, the measurement invariance over time and longitudinal cross-gender invariance was examined. The former used the guidelines by Liu et al. [53], while the latter used ...
Plastid division control: the PDV proteins regulate DRP5B dynamin activity. Plant Mol Biol 82, 255–266. Hoober JK, Eggink LL, Chen M (2007). Chlorophylls, 李保珠等: 植物叶绿体发育及调控研究进展 343 ligands and assembly of light-harvesting complexes in chloroplasts. Photosynth Res 94, 387–...
Such order corresponds to the appearance of solid solution configurations in which the distribution of certain types of atoms is no longer fully uniform, for instance by creation of CMn or NCr pairs, which increases the friction stress. The first dislocation destructs the order by gliding (e.g....
The MH1 ([S]mad homology domain 2) domain is the DBD (DNA-binding domain), which consists of four α-helices and three pairs of β-strands (Fig. 13-6, B). The hydrophobic fourth helix occupies a central position; the other three helices are located on one side and the β-strand...
Two-factor authentication (2FA) verifies a user’s identity by asking for two pieces of proof, such as an online account password and a one-time passcode.
(PWM approach) is provided by a position dependency model (PDM). PDMs consider dependencies between particular pairs of positionsjandlup to a particular distanced, i.e.,d≥|l−j| andl<j. We propose here the use of a special class of PDMs (SLIM models) [26] to estimate the ...
HIF1A was reported as a target of MIR17HG in lung cancer cells, but the specific role of miR-18a in the control of HIF1A expression and activity was not tested [40]. We found that miR-18a, along with other family members encoded by MIR17HG, was downregulated in breast cancer cells ...