Measurements of depressive symptoms Many scales have been used to screen and discern depressive symptoms in large populations. According to previous literature, there is no evidence that one measure is better than the others, and the choice may depend on numerous considerations [7, 16, 17]. For...
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Here we show that the aromatic character of the activation domain of the androgen receptor, a therapeutic target for castration-resistant prostate cancer, is key for its activity as transcription factor, allowing it to translocate to the nucleus and partition into transcriptional condensates upon ...
Values are presented as means ± SEM (n = 6 for male WT and APP/PS1 mice, n = 5 and 7 for female WT and APP/PS1 mice, respectively). c Representative images of PFKFB3 staining in isolated microglia. Scale bars: main figure, 50 μm; magnified image, 10 μm. d The...
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[6] Multi-core is designed to improve performance of certain software products. Not all customers or software applications will necessarily benefit from use of this technology. Performance and clock frequency will vary depending on application workload and your hardware and software configurations. Intel...
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c(2,4,6,8,10))#多维数组 xs<-array(1:24,dim=c(3,4,2))#访问 x1[3]x2[c( 1,3,5)]x3[3:5]xs[ 2,2,2]xs[2,2,1]#增加 x1[6]<-6x2[c(7,9,11)]<-c(11,13,15)#动态增加 x1[length(x1)+1]<-length(x1)+1append(x2,17)x2<-append(x2,17)#修改,凡是能够访问到的地...
9e). Thus, while dosage-sensitive, SOX9-dependent craniofacial genes are generally buffered against SOX9 dosage, those with PRS-like phenotypes and pro-chondrogenic roles are highly sensitive and may mediate the phenotypic specificity of SOX9 dosage perturbation during craniofacial development. Fig. 6:...
Thirteen different variants plus one high frequency SNP (c.304 T > C) were identified of which 6 were novel. In primary erythroblasts, knockdown of endogenous KLF1 resulted in decreased CD44, Lu and increased HbF expression, while KLF1 over-expressing cells were comparable to wild type ...