Evidence for factor IX-independent roles for factor XIa in blood coagulation. J Thromb Haemost. 2013 Dec; 11(12):2118-27.JTAbstract BACKGROUND Factor XIa is traditionally assigned a role in FIX activation during coagulation. However, recent evidence suggests this protea...
Cellulofine, we have isolated a novel blood coagulation factor X-binding protein with anticoagulant activity from the venom of Trimeresurus flavoviridis (Habu... H Atoda,T Morita - 《Journal of Biochemistry》 被引量: 187发表: 1989年 Structure and functions of coagulation factor IX/factor X-bindi...
A method of isolating blood-clotting Factor IX. A solution containing the Factor IX is adsorbed onto an adsorbent carrying &agr;- hydroxylamine groups, and the factor is eluted. The Factor IX from the eluate is adsorbed onto a matrix carrying sulfated carbohydrates, with the conductivity adjusted...
Potential transmission of prions causing Creutzfeldt-Jakob disease (CJD) or its variant form (vCJD) in recipients of blood products was a serious concern early in this century. However, no individual with hemophilia nor any other blood product recipient in the United States is known to have devel...
The blood coagulation factor XIII (FXIII) plays an essential role in the stabilization of fibrin clots. This factor, belonging to the class of transglutaminases, catalyzes the final step of secondary hemostasis, i.e. the crosslinking of fibrin polymers. These crosslinks protect the clots against...
The tissue factor-factor VIIa complex then catalyzes limited proteolysis of two plasma serine protease zymogens (coagulation factors IX and X), converting them to active enzymes and, thus, triggering the blood-clotting cascade. This ultimately leads to the formation of blood clots via a combination...
The bleeding tail was immersed in a 15 mL test tube containing 12 mL pre-warmed PBS. Bleeding time was recorded as the time to cessation of bleeding for 10 s67. Blood loss was quantified by measuring the haemoglobin content of blood collected into PBS. Following centrifugation, the ...
- 《Indian Journal of Hematology & Blood Transfusion》 被引量: 7发表: 2014年 The diversity in clinical presentation of acquired factor V inhibitor. Two case reports. Gelatinous marrow transformation (GMT) is an unusual pathological manifestation of progressive malignant diseases and severe ...
(Factor V Hong Kong) was not associated with APC resistance in the single individual tested with a coagulation screening test.174 The clinical significance of the Arg306Gly mutation is unclear be- cause it was found in a similar percentage of healthy Hong Kong Chinese blood donors (4.5%) and...
Your body can make antibodies against XYNTHA (called “inhibitors”) that may stop XYNTHA from working properly. Your healthcare provider may need to take blood tests from time to time to monitor for inhibitors. Talk to your healthcare provider about any side effect that bothers you or that ...