RES reticuloendothelial system siRNA small interfering RNA 3D three-dimensional TE tissue engineering β-GP β-glycerophosphate Keywords VEGF Drug delivery Growth factor Angiogenesis Regenerative medicine 1. Introduction In instances where a tissue or organ undergoes significant damage, it has the potential...
and thus belong to the well-characterized Cys2His2 family of zinc fingers. Members of the KLF family share zinc finger DNA-binding domains that bind to GC- and CACCC-boxes of DNA, which are found in abundance in thepromoter regionsof many downstream genes, including the KLFs themselves[69...
however, a number of growth-unrelated actions have been recently unravelled [123]. From our perspective IGF-1, GH, and insulin conform a finely regulated axis that inform cells about the nutritional status of the organism so that they can either undergo apoptosis/senescence/quiescence or,...
Video S1. ZBTB16+ ILC Precursors Populated a Niche Defined by Platelet-Derived Growth Factor (PDGFR)α Expressing Fibroblast in the Newborn Lungs, Related to Figure 4 Video S2. ZBTB16 + ILC Precursors Populated a Niche Defined by Platelet-Derived Growth Factor (PDGFR)α Expressing Fibroblast ...
The net outcome of cAMP signaling on PKB activation may be dependent upon the dynamic abundance and distribution of intracellular Epac and PKA (13). These results suggest the observed cell type-specific effects of cAMP can be partially explained by differential expression/distribution of Epac and ...
The abundance of FGF13 mRNA in the telencephalon is declined at P14 (E) and reduced to a low level in adult mice (F). (G) Immunostaining of the E14 mouse cerebral cortex shows that FGF13 is highly expressed in the subplate (SP) and ventricular zone (VZ). (H) FGF13 is enriched ...
Some viral proteins such as VP16 are shown to be important in lytic transcription [56]; therefore, quantifying viral proteins such as VP16 and comparing their abundance in healthy and AD groups could be helpful to determine the role of HSV-1 in AD. Statistics wise, a large sample size ...
bioengineering Article Comparative N-Glycosylation Analysis of the Fc Portions of a Chimeric Human Coagulation Factor VIII and Immunoglobulin G1 Christoph Kannicht *, Mario Kröning, Barbara A. Solecka-Witulska, Guido Kohla and Julia Rosenlöcher Octapharma Biopharmaceuticals GmbH, Molecular ...
Stoner, G.L.; Agostini, H.T.; Ryschkewitsch, C.F.; Komoly, S. JC virus excreted by multiple sclerosis patients and paired controls from Hungary. Mult. Scler. J. 1998, 4, 45–48. [Google Scholar] [CrossRef] [PubMed] Sundsfjord, A.; Osei, A.; Rosenqvist, H.; Van Ghelue, M...
If ATF4 requires a dimerization partner, the abundance of that protein is not limiting, even in the basal or “fed” state. Support for this hypothesis comes from the use of HEK293 cells stably expressing a tetracycline (Tet)-inducible ATF4 construct (56). Tet-induced ATF4 expression in ...