BMC Infectious Diseases (2024) 24:1256 https://doi.org/10.1186/s12879-024-10143-3 BMC Infectious Diseases REVIEW Open Access Review of the novel antifungal drug olorofim (F901318) Yuri Vanbiervliet1*† , Tine Van Nieuwenhuyse2† , Robina Aerts1 , Katrien Lagrou3 , Isabel...
Olorofim shows a unique spectrum of activity.A schematic overview is shown inFig.2. This unique spectrum of activity of olorofim has been attributed to differences in the DHODH enzymes among various groups of fungi [59]. Despite their classification as class II DHODH enzymes, those derived fr...
Olorofim is a novel antifungal agent with in vitro activity against Aspergillus and some other molds. Here, we addressed technical aspects for EUCAST olorofim testing and generated contemporary MIC data. EUCAST E.Def 9.3.1 testing was performed comparing two plate preparation methods (serial ...