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Du Y, Rosqvist R, Forsberg A (2002) Role of fraction 1 antigen of Yersinia pestis in inhibition of phagocytosis. Infect Immun 70:1453–1460 CrossRef Fields KA, Nilles ML, Cowan C, Straley SC (1999) Virulence role of V antigen of Yersinia pestis at the bacterial surface. Infect Immun...
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F: package/ctorrent/ N: Oleksandr Zhadan <oleks@arcturusnetworks.com> F: board/arcturus/ F: configs/arcturus_ucp1020_defconfig F: configs/arcturus_ucls1012a_defconfig N: Oli Vogt <oli.vogt.pub01@gmail.com> F: package/python-django/ F: package/python-flup/ N: Olivier Matz ...
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在TMIon Torrent 测序中,DNA被剪切成大约300到800个碱基对的片段,并且这些片段是平端的。然后将寡核苷酸衔接子连接到片段的末端。衔接子充当用于片段的扩增和测序的引物。片段可附着到表面,并以使得这些片段可个别地解析的解析度附着。一个或多个核苷酸的+添加释放了质子(H),在测序仪器中检测并记录其信号。信号...
2002年,EMEA的专利药物委员会(Committee for Proprietary Medicinal Products,CPMP;现人用药物委员会Committee for Human Medicinal Products,CHMP)发布关于基因毒性杂质的意见书[3]。该意见书按照杂质是否存在有证据的阈值而将基因毒性杂质进行分类:①有足够的研究证据支持其阈...
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辉瑞万艾可的美国基本专利已于2012年到期,FDA数据显示,目前已有梯瓦、迈兰、Apotex、Torrent、Actavis、Amneal、Macleods、Watson Labs、雷迪博士、Hetero Labs等多家企业获得批准。早前,万艾可在韩国及泰国专利到期后,销量锐减,为了应对仿制药的冲击,辉瑞在美国市场联手CVS推...