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Recently, there has been a promising revival of gene therapy for diseases with unmet therapeutic needs. To date, most gene therapies have used viral-based ubiquitous promoters–however, promoters that restrict expression to target cells will minimize off-target side effects, broaden the palette of ...
Small promoters that recapitulate endogenous gene expression patterns are important for basic, preclinical, and now clinical research. Recently, there has been a promising revival of gene therapy for diseases with unmet therapeutic needs. To date, most g
Download: Download full-size image Fig. 1.– Comparison of students’ responses to questions pertaining to their engagement with the course and their perception of the course demands. Violin plots showing a smoothed distribution of students’ responses to Questions 1 (A), 2 (B), and 3 (D)....
Given the large, fixed initial outlay that image intensifiers require, where do the experts think that the sweet spot for getting into NV is for newbies like me who are progressing in the hobby? Jeff and Eddgie seem like they've had one of everything before, but with your experience, whe...
if double vision comes and goes and there are other symptoms of possible nervous system dysfunction,myasthenia gravisandmultiple sclerosisare among the likely causes. If the eyes do not point in the same direction, the direction of gaze in which double vision occurs sometimes indicates which cranial...
S. (2003). Discordant expression of the sterol pathway in lens underlies simvastatin-induced cataracts in Chbb: Thom rats. Journal of Lipid Research, 44, 198–211. Article CAS PubMed Google Scholar Pyrah, I. T., Kalinowski, A., Jackson, D., Davies, W., Davis, S., Aldridge, A.,...
The visual task consists in searching for a unique number "5" embedded in an image of numbers between "1" and "9", as depicted in Fig. 1A. We randomly place the numbers at the nodes posi- tions of a regular square lattice and displace them from that position by a small random ...
mentioned that we don’t get free tea and coffee in Leeds, the tea lady promptly replied in a thick, wonderful scouse accent “don’t worry love, you’re in Liverpool now, we’ll look after you.” My reply (in an equally thick scouse accent) “Ahhhhhh ta very much love… ta-rah!
Electromagnetic radiation at wavelengths between 400 and 750 nm is perceived by humans as light. The light source most important to us is the sun. In a rainbow, we see the yellowish-white light of the sun separated into its components, the spectrum of wa