The proportion of women giving birth after the age of 45 has increased significantly over the last several decades for a multitude of reasons. We set out to describe perinatal outcomes for women as pregnancy progresses from advanced (35 or older) to extremely advanced maternal age (45 or older...
1,19 Maternal age was defined as the age of the biological mother at the time of delivery. The timing of rupture of membranes was noted. Antenatal antibiotic use was defined as the administration of any antibiotics to the mother during the admission that resulted in delivery. Antenatal ...
Other novel areas that warrant further study include advanced brain imaging to better understand injury, repair, and growth; minimally invasive delivery of aerosolized surfactant; tissue-engineering and regenerative medicine; and selected growth factors and cellular therapies. Although survival of extremely ...
The two groups were excluded from the trial because the mothers had received betamethasone for greater than 24 hours prior to delivery or because, on admission to the hospital, labor was too far advanced for proper informed consent to enter the trial. Attempts were made to delay delivery of ...
A molecular signature of severe FIR Advanced histological patterns of FIR are associated with peri- natal brain damage (17); therefore, gene expression profiles of UC tissue from infants with "severe FIR" can potentially shed light on molecular mechanisms leading to adverse neuro- logical outcome....
In high-income countries, EPIs care is more advanced. A multicenter study in the United States revealed that out of 10,877 infants born at a gesta- tional age of 22–28 weeks between 2013 and 2018 [5], the survival rate at discharge was 78.3%, and the survival rate at the discharge ...
While our ability to observe the dynamics of developmental processes has greatly advanced, tools to perturb the proteins underlying these processes at the required temporal resolution and efficiency are lacking in animal models. Here, we present iLEXY, which can fill this gap for nuclear proteins. ...
Dopamine, dobu- tamine, epinephrine, and hydrocortisone were initiated in that order and advanced to a set maximum amount to maintain mean arterial pressure >25 mm Hg. A weaning protocol was followed as well to avoid hypertension. Sepsis was defined by at least one positive blood, urine, ...
Childhood depression can be addressed preventively Depression is a common psychiatric disorder that has been reported to affect 1-2 percent of preschool and prepubertal children and 3-8 percent of adolescents. However, childhood depression is a severe disorder and its prevention can be advanced with...
Yogev Y, Melamed N, Bardin R, Tenenbaum-Gavish K, Ben-Shitrit G, and Ben- Haroush A (2010) Pregnancy outcome at extremely advanced maternal age. Am J Obstet Gynecol, 203, 558-7.Yogev Y, Melamed N, Bardin R, Tenenbaum-Gavish K, Ben- Shitrit G, Ben-Haroush A. Pregnancy outcome at...