The extracellular matrix (ECM) is one of the major components of tumors that plays multiple crucial roles, including mechanical support, modulation of the microenvironment, and a source of signaling molecules. The quantity and cross-linking status of ECM components are major factors determining tissue...
We used immunoperoxidase staining and double immunofluorescent staining to demonstrate the macromolecular components of the extracellular matrix of the lamina cribrosa from young human donors. The cribriform plates were made up of a core of elastin fibers with a sparse, patchy distribution of collagen ...
Described are preferred extracellular matrix composites including a first extracellular matrix material having a second extracellular matrix material deposited thereon. The preferred materials are made by culturing cells in contact with an extracellular matrix graft material in a fashion to cause the cells ...
Cellular phenotypes and molecular functions are fundamentally dependent on signals from outside the cell such as the interactions with the extracellular matrix (ECM). The core matrisome is composed of ~300 unique matrix macromolecules and can be classified into collagens, proteoglycans (such as heparan...
ayou want( )sandwich 正在翻译,请等待...[translate] ait will make me try to offer help where it is possible 它将做我尝试提供帮助,它是可能的[translate] aexcrete sufficient amount of extracellular matrix, etc.; 排泄充足的相当数量细胞外矩阵等等;[translate]...
2B), involved in degradation of extracellular matrix and collagen, and associated with musculoskeletal system disease and inflammatory response (Fig. 2C). A majority (84.9%) of the SF EV proteinsSF>PL were functionally and physically linked with each other in the network (protein-protein ...
The extracellular matrix (ECM) is a three-dimensional scaffold holding cells in a specific space and ensures tissue stability [[1], [2], [3]]. ECM is produced by all types of cells but its composition is specific for each type of tissue [1,2]. Regardless of the origin, extracellular ...
fromflowingbackwardsintotheheartinsteadofforwardtowardsthesystemiccirculationandthelungs.Theabilityofheartvalvestoopenandcloserepeatedly,aswellasthemaintenanceofthephenotypesofvalvularcells,ismadepossiblebytheirtissuemicrostructure,specificallythecompositionandorientationofextracellularmatrix(ECM).TheECMwithinheartvalvesis...
Biofilms, surface-attached communities of bacteria encased in an extracellular matrix, are a major mode of bacterial life. How the material properties of the matrix contribute to biofilm growth and robustness is largely unexplored, in particular in respo
The ability to recreate an optimal cellular microenvironment is critical to understand neuronal behavior and functionality in vitro. An organized neural extracellular matrix (nECM) promotes neural cell adhesion, proliferation and differentiation. Here, we expanded previous observations on the ability of nEC...